| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SAP (Serum Amyloid P) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
ELISA, IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5-1ug/ml, 5ug/ml, ELISA: 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the SAP antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This SAP antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
20219 |
| Purity: |
Antigen affinity |
| Description: |
It belongs to the pentraxins family, It has been demonstrated that this protein binds to apoptotic cells at an early stage, The binding of SAP to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone, This gene is mapped to 1q23, This protein is also thought to control the degradation of chromatin, a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called amyloid, also known as PTX2 or APCS, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins, is the identical serum form of amyloid P component (AP), serum (SAP), which raises the possibility that it is involved in dealing with apoptotic cells in vivo, 2, Amyloid P component |
| Immunogen: |
Mouse partial recombinant protein (AA 21-224) was used as the immunogen for this Serum Amyloid P antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SAP antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Group: |
Sera |
| Gene target: |
SAP Amyloid P) |
| Short name: |
SAP Antibody (Serum Amyloid P) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SAP (Antibody to) (blood serum Amyloid P) |
| Alternative technique: |
antibodies |
| Identity: |
584 |
| Gene: |
APCS |
More about : APCS |
| Long gene name: |
amyloid P component, serum |
| Synonyms: |
SAP PTX2 MGC88159 |
| Synonyms name: |
pentraxin-related 9, 5S alpha-1-glycoprotein pentraxin-2 |
| Locus: |
1q23, 2 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
325 |
| Pubmed identfication: |
2987268 |
| RefSeq identity: |
NM_001639 |
| Classification: |
Short pentraxins |
| Havana BLAST/BLAT: |
OTTHUMG00000022741 |