| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IHH (Indian Hedgehog) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the IHH antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This IHH antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q14623 |
| Purity: |
Antigen affinity |
| Description: |
Hedgehog proteins are essential regulators of a variety of developmental processes including growth, Mutations in this gene are also the cause of acrocapitofemoral dysplasia, Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges, The encoded protein specifically plays a role in bone growth a differentiation, This gene encodes a member of the hedgehog family of secreted signaling molecules, also known as IHH or HHG2 is a protein which in humans is encoded by the IHH gene, patterning and morphogenesis, Indian hedgehog |
| Immunogen: |
An amino acid sequence from the C-terminus of human Indian Hedgehog (EPHRLRAFQVIETQD) was used as the immunogen for this IHH antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IHH antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IHH (Indian Hedgehog) |
| Short name: |
IHH Antibody (Indian Hedgehog) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Indian hedgehog (Antibody to) (Indian Hedgehog) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BDA1 and HHG2, BT, Extracellular, IHH and IDBG-81274 and ENSG00000163501 and 3549, Ihh and IDBG-169082 and ENSMUSG00000006538 and 16147, peptidase activity, this GO :0001501 and skeletal system development and biological process this GO :0001503 and ossification and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001708 and cell fate specification and biological process this GO :0001763 and morphogenesis of a branching structure and biological process this GO :0001944 and vasculature development and biological process this GO :0001947 and heart looping and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003382 and epithelial cell morphogenesis and biological process this GO :0003406 and retinal pigment epithelium development and biological process this GO :0005113 and patched binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006029 and proteoglycan metabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0007154 and cell communication and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007389 and pattern specification process and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0016539 and intein-mediated protein splicing and biological process this GO :0030154 and cell differentiation and biological process this GO :0030704 and vitelline membrane formation and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0031016 and pancreas development and biological process this GO :0032332 and positive regulation of chondrocyte differentiation and biological process this GO :0032355 and response to estradiol and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0033085 and negative regulation of T cell differentiation in thymus and biological process this GO :0033088 and negative regulation of immature T cell proliferation in thymus and biological process this GO :0033089 and positive regulation of T cell differentiation in thymus and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0035988 and chondrocyte proliferation and biological process this GO :0040008 and regulation of growth and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045453 and bone resorption and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045880 and positive regulation of smoothened signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0046639 and negative regulation of alpha-beta T cell differentiation and biological process this GO :0048074 and negative regulation of eye pigmentation and biological process this GO :0048469 and cell maturation and biological process this GO :0048557 and embryonic digestive tract morphogenesis and biological process this GO :0048596 and embryonic camera-type eye morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048745 and smooth muscle tissue development and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0051216 and cartilage development and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0060220 and camera-type eye photoreceptor cell fate commitment and biological process this GO :0060323 and head morphogenesis and biological process this GO :0061053 and somite development and biological process this GO :0072498 and embryonic skeletal joint development and biological process this GO :0090136 and epithelial cell-cell adhesion and biological process, this GO :0005113 : patched binding, this GO :0005113 : patched binding and also this GO :0005509 : calcium ion binding and also this GO :0008233 : peptidase activity, this GO :0005509 : calcium ion binding, this GO :0008233 : peptidase activity, 22104 and IDBG-643926 and ENSBTAG00000008452 and 522714, Indian hedgehog |
| Identity: |
5956 |
| Gene: |
IHH |
More about : IHH |
| Long gene name: |
indian hedgehog |
| Synonyms gene name: |
Indian hedgehog (Drosophila) homolog Indian hedgehog homolog (Drosophila) |
| Synonyms: |
HHG2 BDA1 |
| Locus: |
2q35 |
| Discovery year: |
1995-03-21 |
| GenBank acession: |
L38517 |
| Entrez gene record: |
3549 |
| Pubmed identfication: |
7590746 14770182 |
| RefSeq identity: |
NM_002181 |
| Havana BLAST/BLAT: |
OTTHUMG00000154631 |