| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SERPINA3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the SERPINA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This SERPINA3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P01011 |
| Purity: |
Antigen affinity |
| Description: |
In humans, Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease, Polymorphisms in this protein appear to be tissue specific and influence protease targeting, The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class, This gene is mapped to 14q32, Variations in this protein's sequence have been implicated in Alzheimers disease, also called serpin peptidase inhibitor, and deficiency of this protein has been associated with liver disease, antitrypsin), clade A (alpha-1 antiproteinase, is an alpha globulin glycoprotein that is a member of the serpin superfamily, it is encoded by the SERPINA3 gene, member 3 or GIG24, 13, Alpha 1-antichymotrypsin |
| Immunogen: |
An amino acid sequence from the middle region of human SERPINA3 (EMPFDPQDTHQSRFY) was used as the immunogen for this SERPINA3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SERPINA3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SERPINA3 |
| Short name: |
SERPINA3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antitrypsin), clade A (a-1 antiproteinase, member 3 (Antibody to), serpin peptidase inhibitor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
SERPINA3 and IDBG-18406 and ENSG00000196136 and 12, antitrypsin), clade A (alpha-1 antiproteinase, member 3, nuclei, protein binding, this GO :0003677 and DNA binding and molecular function this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0006953 and acute-phase response and biological process this GO :0006954 and inflammatory response and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0019216 and regulation of lipid metabolic process and biological process this GO :0030162 and regulation of proteolysis and biological process this GO :0030277 and maintenance of gastrointestinal epithelium and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072562 and blood microparticle and cellular component, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0005515 : protein binding, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0005515 : protein binding, serpin peptidase inhibitor |
| Identity: |
16 |
| Gene: |
SERPINA3 |
More about : SERPINA3 |
| Long gene name: |
serpin family A member 3 |
| Synonyms gene: |
AACT |
| Synonyms gene name: |
alpha-1-antichymotrypsin serine (or cysteine) proteinase inhibitor, antitrypsin), antitrypsin), clade A (alpha-1 antiproteinase, clade A (alpha-1 antiproteinase, member 3 , member 3 serpin peptidase inhibitor |
| Synonyms: |
ACT |
| Locus: |
14q32, 13 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
K01500 |
| Entrez gene record: |
12 |
| Pubmed identfication: |
3260956 24172014 |
| RefSeq identity: |
NM_001085 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000029851 |