| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HNF6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the HNF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This HNF6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UBC0 |
| Purity: |
Antigen affinity |
| Description: |
Expression of the encoded protein is enriched in the liver, The gene encodes a member of the Cut homeobox family of transcription factors, This gene may influence a variety of cellular processes including glucose metabolism, also called Hepatocyte nuclear factor 6 (HNF6) is found strong expression in liver and lower expression in testis and skin, and antagonizes glucocorticoid-stimulated gene transcription, and it may also be associated with cancer, cell cycle regulation, where it stimulates transcription of liver-expressed genes, One cut homeobox 1 (ONECUT1) |
| Immunogen: |
mouse and rat), An amino acid sequence from the N-terminus of human ONECUT1/HNF6 (LGSIHNSQQGLPHYAHP) was used as the immunogen for this HNF6 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HNF6 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HNF6 |
| Short name: |
HNF6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HNF6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8138 |
| Gene: |
ONECUT1 |
More about : ONECUT1 |
| Long gene name: |
one cut homeobox 1 |
| Synonyms gene: |
HNF6 HNF6A |
| Synonyms gene name: |
family member 1 , one cut domain |
| Synonyms: |
HNF-6 |
| Locus: |
15q21, 3 |
| Discovery year: |
2000-02-11 |
| GenBank acession: |
U77975 |
| Entrez gene record: |
3175 |
| Pubmed identfication: |
8887657 8790352 |
| Classification: |
CUT class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000131899 |