| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MMP24 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the MMP24 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This MMP24 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9Y5R2 |
| Purity: |
Antigen affinity |
| Description: |
However, Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases, Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, The gene has previously been referred to as MMP25 but has been renamed MMP24, This gene may be a proteoglycanase involved in degradation of proteoglycans, This protein activates MMP2 by cleavage, also known as MT5MMP and previously as MMP25, and tissue remodeling, as well as in disease processes, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted, is an enzyme that in humans is encoded by the MMP24 gene, reproduction, such as arthritis and metastasis, such as dermatan sulfate and chondroitin sulfate proteoglycans, such as embryonic development, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, Matrix metalloproteinase-24 |
| Immunogen: |
mouse and rat), An amino acid sequence from the N-terminus of human Matrix metalloproteinase-24 (YHEIKSDRKEADIMIFFA) was used as the immunogen for this MMP24 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MMP24 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MMP24 |
| Short name: |
MMP24 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MMP24 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7172 |
| Gene: |
MMP24 |
More about : MMP24 |
| Long gene name: |
matrix metallopeptidase 24 |
| Synonyms gene name: |
matrix metalloproteinase 24 (membrane-inserted) matrix metallopeptidase 24 (membrane-inserted) |
| Synonyms: |
MT5-MMP |
| Synonyms name: |
membrane-type 5 matrix metalloproteinase |
| Locus: |
20q11, 22 |
| Discovery year: |
1999-08-06 |
| GenBank acession: |
AF131284 |
| Entrez gene record: |
10893 |
| Pubmed identfication: |
10363975 |
| RefSeq identity: |
NM_006690 |
| Classification: |
Matrix metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000032330 |