| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRAF5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the TRAF5 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TRAF5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O00463 |
| Purity: |
Antigen affinity |
| Description: |
Fluorescence in situ hybridization confirmed the regional localization of human TRAF5 to chromosome 1q32, It is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases, It seems to be involved in apoptosis, The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor(TRAF) protein family, This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation, also known as RNF84, is a protein that in humans is encoded by the TRAF5 gene, 2-q32, 3, TNF receptor-associated factor 5 |
| Immunogen: |
An amino acid sequence from the N-terminus of human TNF receptor-associated factor 5 (HRFCQHCILSLREL) was used as the immunogen for this TRAF5 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRAF5 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRAF5 |
| Short name: |
TRAF5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
tumor necrosis factor receptor-associated factor 5 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
MGC:39780 and RNF84, Plasma membranes, TRAF5 and IDBG-106494 and ENSG00000082512 and 7188, TRAF5 and IDBG-638230 and ENSBTAG00000012020 and 507234, Traf5 and IDBG-208924 and ENSMUSG00000026637 and, thioesterase binding, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0035631 and CD40 receptor complex and cellular component this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0004871 : signal transducer activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031996 : thioesterase binding, this GO :0004871 : signal transducer activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031996 : thioesterase binding, TNF receptor-associated factor 5 |
| Identity: |
12035 |
| Gene: |
TRAF5 |
More about : TRAF5 |
| Long gene name: |
TNF receptor associated factor 5 |
| Synonyms: |
RNF84 |
| Locus: |
1q32, 3 |
| Discovery year: |
1997-02-03 |
| GenBank acession: |
AB000509 |
| Entrez gene record: |
7188 |
| Pubmed identfication: |
9126477 |
| RefSeq identity: |
NM_004619 |
| Classification: |
Ring finger proteins TNF receptor associated factors |
| Havana BLAST/BLAT: |
OTTHUMG00000036997 |