| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cdk6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Cdk6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Cdk6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q00534 |
| Purity: |
Antigen affinity |
| Description: |
Cdk6 also plays a role in promoting the proliferation of beta-cells in pancreatic islets of Langerhans, It prevents cell proliferation and regulates negatively cell differentiation, Radiation hybrid analysis and inclusion within a mapped clone place the gene at 7q21, Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation and promotes G1/S transition, The protein encoded by this gene is a member of the cyclin-dependent protein kinase(CDK) family, This gene also involved in initiation and maintenance of cell cycle exit during cell differentiation, also called Plstire, but is required for the proliferation of specific cell types, is an enzyme that in humans is encoded by the CDK6 gene, Cell division protein kinase 6 |
| Immunogen: |
An amino acid sequence from the C-terminus of human Cell division protein kinase 6 (AYSALSHPYFQDLERCKENL) was used as the immunogen for this Cdk6 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cdk6 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cdk6 |
| Short name: |
Cdk6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cdk6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1777 |
| Gene: |
CDK6 |
More about : CDK6 |
| Long gene name: |
cyclin dependent kinase 6 |
| Synonyms: |
PLSTIRE |
| Locus: |
7q21, 2 |
| Discovery year: |
1994-02-14 |
| Entrez gene record: |
1021 |
| Pubmed identfication: |
1639063 |
| Classification: |
Cyclin dependent kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000131697 |
| Locus Specific Databases: |
LRG_991 |