| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MADCAM1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the MADCAM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This MADCAM1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13477 |
| Purity: |
Antigen affinity |
| Description: |
By PCR-based analysis of somatic cell hybrids, It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1, L-selectin, Leung et al, The protein encoded by this gene is an endothelil cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1(alpha4 / beta7), and VLA-4(alpha4/beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues, (1997) mapped the gene to chromosome 19, Mucosal Vascular Addressin Cell Adhesion Molecule 1 is a protein that in humans is encoded by the MADCAM1 gene |
| Immunogen: |
An amino acid sequence from the middle region of human MADCAM1 (EEPQGDEDVLFRVTERWR) was used as the immunogen for this MADCAM1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MADCAM1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MADCAM1 |
| Short name: |
MADCAM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
mucosal vascular addressin cellular adhesion molecule 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, MACAM1, MADCAM1 and IDBG-12208 and ENSG00000099866 and 8174, Madcam1 and IDBG-170375 and ENSMUSG00000020310 and 17123, Plasma membranes, protein binding, this GO :0002687 and positive regulation of leukocyte migration and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007568 and aging and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030216 and keratinocyte differentiation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050900 and leukocyte migration and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, 46202 and IDBG-645471 and ENSBTAG00000039355 and 527275, 789849, mucosal vascular addressin cell adhesion molecule 1 |
| Identity: |
6765 |
| Gene: |
MADCAM1 |
More about : MADCAM1 |
| Long gene name: |
mucosal vascular addressin cell adhesion molecule 1 |
| Synonyms: |
MACAM1 |
| Synonyms name: |
mucosal addressin cell adhesion molecule-1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2000-02-11 |
| GenBank acession: |
U43628 |
| Entrez gene record: |
8174 |
| Pubmed identfication: |
9162097 8609404 |
| RefSeq identity: |
NM_130760 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180548 |