| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IKKb |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the IKKb antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This IKKb antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O14920 |
| Purity: |
Antigen affinity |
| Description: |
Beta), Kinase of, Mercurio et al, NFKBIKB, Shindo et al, They demonstrated that aspirin and sodium salicylate specifically inhibit IKK beta activity in vitro and in vivo by binding to IKK beta to reduce ATP binding, Yin et al, also known as IKKb, and IKK2, is a protein that in humans is encoded by the IKBKB gene, (1997) found that mutations in IKK2/IKKb had a more pronounced effect upon NFKB activation than did comparable mutations in <, (1998) mapped the gene to chromosome 8p12-p11 by FISH, (1998) tested the activity of various antiinflammatory agents on the IKK complex, /a>, /search_result, IKBKB (Inhibitor of Kappa Light Chain Gene Enhancer in B Cells, IKK1/IKKa<, a href=, php?search_txt=ikk%20alpha> |
| Immunogen: |
An amino acid sequence from the C-terminus of human IKK beta (QEMVRLLLQAIQSFEKK) was used as the immunogen for this IKKb antibody (100% mouse homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IKKb antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IKKb |
| Short name: |
IKKb Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IKKb (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5960 |
| Gene: |
IKBKB |
More about : IKBKB |
| Long gene name: |
inhibitor of nuclear factor kappa B kinase subunit beta |
| Synonyms gene name: |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| Synonyms: |
IKK2 NFKBIKB IKK-beta IKKB |
| Locus: |
8p11, 21 |
| Discovery year: |
1998-02-11 |
| GenBank acession: |
AF029684 |
| Entrez gene record: |
3551 |
| Pubmed identfication: |
9878263 9763654 18308615 |
| Havana BLAST/BLAT: |
OTTHUMG00000164092 |