| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Tec |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Tec antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Tec antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P42680 |
| Purity: |
Antigen affinity |
| Description: |
By fluorescence in situ hybridization, Hantschel et al, Mouse Tec is a non-receptor type protein-tyrosine kinase that is highly expressed in many hematopoietic cell lines, Sato et al, The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain, is an enzyme that in humans is encoded by the TEC gene, the same location reported for TXK, which is used for treatment of BCR/ABL-positive CML, (1994) mapped the gene to 4p12, (2007) identified TEC kinase and BTK kinase as major binders of the tyrosine kinase inhibitor dasatinib, TEC Protein Tyrosine Kinase |
| Immunogen: |
Amino acids 612-631 (FEDLLRTIDELVECEETFGR-human) were used as the immunogen for this Tec antibody (100% rat homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Tec antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Tec |
| Short name: |
Tec Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
tec protein tyrosine kinase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11719 |
| Gene: |
TEC |
More about : TEC |
| Long gene name: |
tec protein tyrosine kinase |
| Synonyms: |
PSCTK4 |
| Locus: |
4p12-p11 |
| Discovery year: |
1994-12-15 |
| GenBank acession: |
D29767 |
| Entrez gene record: |
7006 |
| Pubmed identfication: |
7934162 |
| Classification: |
Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000128623 |