| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
VEGFR2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the VEGFR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This VEGFR2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35968 |
| Purity: |
Antigen affinity |
| Description: |
1991), 1993), Flk1 is the mouse homolog of KDR(Matthews et al, Its expression is upregulated by hypoxia, KDR is the human gene encoding it, Sait et al, VEGFR or VEGFR2, Vascular endothelial growth factor(VEGF) is the only mitogen that specifically acts on endothelial cells, also known as FLK1, and its cell-surface receptor, is a VEGF receptor, is exclusively expressed in endothelial cells(Plate et al, known as fetal liver kinase-1(Flk1) in mouse, thus indicating the location of a cluster of receptor tyrosine kinase genes, (1995) likewise corrected the assignment to chromosome 4q11-q12 to the same region occupied also by PDGFRA and KIT, KDR(Kinase Insert Domain Receptor) |
| Immunogen: |
An amino acid sequence from the middle region of human VEGF Receptor 2 (HHIHWYWQLEEECANE) was used as the immunogen for this VEGFR2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the VEGFR2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
VEGFR2 |
| Short name: |
VEGFR2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
VEGFR2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6307 |
| Gene: |
KDR |
More about : KDR |
| Long gene name: |
kinase insert domain receptor |
| Synonyms gene name: |
kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Synonyms: |
FLK1 VEGFR VEGFR2 CD309 |
| Synonyms name: |
vascular endothelial growth factor receptor 2 fetal liver kinase 1 |
| Locus: |
4q12 |
| Discovery year: |
1991-07-10 |
| GenBank acession: |
AF035121 |
| Entrez gene record: |
3791 |
| Pubmed identfication: |
1417831 |
| Classification: |
I-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000128734 |
| Locus Specific Databases: |
The Globin Gene Server |