| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LTBR |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the LTBR antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This LTBR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P36941 |
| Purity: |
Antigen affinity |
| Description: |
By linkage analysis with recombinant inbred mouse strains, Lo et al, Nakamura et al, Presumably, Silva-Santos et al, also called TNFCR or LT-BETA-R, as critical regulators of key enzymes that control lipid metabolism, is a receptor for lymphotoxin which in humans is encoded by the LTBR gene, the human homolog is located on 12p13, tumor necrosis factor cytokine family members that are primarily expressed on lymphocytes, (1995) demonstrated that the Tnfcr locus is close to the Tnfr1 gene on mouse chromosome 6, (2005) reported that double-positive T cells regulate the differentiation of early thymocyte progenitors and gamma-delta cells by a mechanism dependent on the transcription factor ROR-gamma-t and LTBR, (2007) identified lymphotoxin and LIGHT (TNFSF14), Lymphotoxin B Receptor |
| Immunogen: |
An amino acid sequence from the C-terminus of human Lymphotoxin B Receptor (ATPSNRGPRNQFITHD) was used as the immunogen for this LTBR antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the LTBR antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
LTBR |
| Short name: |
LTBR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 3) (Antibody to), lymphotoxin b receptor (TNFR superfamily |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD18 and D12S370 and LT-BETA-R and TNF-R-III and TNFCR and TNFR-RP and TNFR2-RP and TNFR3 and TNFRSF3, LTBR and IDBG-13973 and ENSG00000111321 and 102724071, LTBR and IDBG-640501 and ENSBTAG00000015312 and 504653, Ltbr and IDBG-189788 and ENSMUSG00000030339 and 17000, Plasma membranes, identical protein binding, member 3), this GO :0005515 and protein binding and molecular function this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0042802 : identical protein binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0042802 : identical protein binding, 4055, lymphotoxin beta receptor (TNFR superfamily |
| Identity: |
6718 |
| Gene: |
LTBR |
More about : LTBR |
| Long gene name: |
lymphotoxin beta receptor |
| Synonyms gene: |
D12S370 |
| Synonyms: |
TNFCR TNFR-RP TNFR2-RP TNF-R-III TNFRSF3 |
| Synonyms name: |
TNFR superfamily, member 3 |
| Locus: |
12p13 |
| Discovery year: |
1996-03-12 |
| GenBank acession: |
L04270 |
| Entrez gene record: |
4055 |
| Pubmed identfication: |
8171323 8486360 |
| Classification: |
Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000168356 |