| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Aquaporin 4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Aquaporin 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This Aquaporin 4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P55087 |
| Purity: |
Antigen affinity |
| Description: |
AQP4 is the predominant water channel in the brain and has an important role in brain water homeostasis, Analyzing the expression of AQP4 in mammalian skeletal muscle, By fluorescence in situ hybridization, By interspecific backcross analysis, Frigeri et al, Immunocytochemistry revealed strong AQP4 water channel expression in Muller cells in mouse retina and in fibrous astrocytes in optic nerve, Lu et al, The aquaporins are a family of water-selective membrane channels found in animals, Turtzo et al, affinity-purified AQP4 antibodies stained selectively the sarcolemma of fast-twitch fibers, also known as Mercurial-Insensitive Water Channel (MIWC), and microorganisms, in immunohistochemical experiments, is protein which in humans is encoded by the AQP4 gene, plants, (1996) determined that the AQP4 gene maps to 18q11, (1997) mapped the mouse Aqp4 gene to the proximal region of chromosome 18, (1998) found that, 1, 2-q12, Aquaporin 4 |
| Immunogen: |
Amino acids 258-27 (FKRRFKEAFSKAAQQTK) were used as the immunogen for this Aquaporin 4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Aquaporin 4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Aquaporin 4 |
| Short name: |
Aquaporin 4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Aquaporin 4 (Antibody to) |
| Alternative technique: |
antibodies |