| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FES |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the FES antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This FES antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P07332 |
| Purity: |
Antigen affinity |
| Description: |
A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified, Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia, Non-onc intervening sequences were present in the human counterpart, The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation, This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities, but it is also involved in normal hematopoiesis, Feline sarcoma oncogene is an enzyme that in humans is encoded by the FES gene |
| Immunogen: |
An amino acid sequence from the C-terminus of human Feline sarcoma oncogene (STIYQELQSIRKRHR) was used as the immunogen for this FES antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FES antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FES |
| Short name: |
FES Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FES (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3657 |
| Gene: |
FES |
More about : FES |
| Long gene name: |
FES proto-oncogene, tyrosine kinase |
| Synonyms gene name: |
feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog feline sarcoma oncogene |
| Synonyms: |
FPS |
| Synonyms name: |
Oncogene FES, feline sarcoma virus c-fes/fps protein |
| Locus: |
15q26, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X52192 |
| Entrez gene record: |
2242 |
| Pubmed identfication: |
1870997 |
| RefSeq identity: |
NM_002005 |
| Classification: |
SH2 domain containing F-BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000044456 |