| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Peroxiredoxin 2 (PRDX2) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Peroxiredoxin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Peroxiredoxin 2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P32119 |
| Purity: |
Antigen affinity |
| Description: |
Choi et al, PRDX2 accounted for about half of the thioredoxin activity in parasite extracts, PRP, PRX2, PRXII or TPX1, Prx II deficiency results in increased production of peroxide, The Prdx2-/- mice were healthy in appearance and fertile, The encoded protein may play an antioxidant protective role in cells, This gene encodes a member of a family of antioxidant enzymes which reduce hydrogen peroxide and alkyl hydroperoxides, This protein may have a proliferative effect and play a role in cancer development or progression, also known as NKEFB, and expression was increased in the presence of chloroquine, and may contribute to the antiviral activity of CD8(+) T-cells, and subsequently increased cell proliferation and migration in response to PDGF, enhanced activation of PDGF receptor and phospholipase C-gamma-1, falciparum strain susceptibility to the drug, is aproteinthat in humans is encoded by the PRDX2 gene, regardless of P, (2005)demonstrated that PRDX2 is a negative regulator of PDGF signaling, Peroxiredoxin 2 |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human PRDX2 (DTIKPNVDDSKEYFSKHN) was used as the immunogen for this Peroxiredoxin 2 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Peroxiredoxin 2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Peroxiredoxin 2 (PRDX2) |
| Short name: |
Peroxiredoxin 2 Antibody (PRDX2) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Peroxiredoxin 2 (Antibody to) (peroxiredoxin 2) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, HEL-S-2a and NKEF-B and NKEFB and PRP and PRX2 and PRXII and PTX1 and TDPX1 and TPX1 and TSA, PRDX2 and IDBG-31024 and ENSG00000167815 and 7001, PRDX2 and IDBG-642937 and ENSBTAG00000012062 and 286793, peroxiredoxin activity, this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006979 and response to oxidative stress and biological process this GO :0008379 and thioredoxin peroxidase activity and molecular function this GO :0016209 and antioxidant activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0019430 and removal of superoxide radicals and biological process this GO :0034599 and cellular response to oxidative stress and biological process this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0051920 and peroxiredoxin activity and molecular function this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0008379 : thioredoxin peroxidase activity, this GO :0008379 : thioredoxin peroxidase activity and also this GO :0016209 : antioxidant activity and also this GO :0016491 : oxidoreductase activity and also this GO :0051920 : peroxiredoxin activity, this GO :0016209 : antioxidant activity, this GO :0016491 : oxidoreductase activity, this GO :0051920 : peroxiredoxin activity, peroxiredoxin 2 |
| Identity: |
9353 |
| Gene: |
PRDX2 |
More about : PRDX2 |
| Long gene name: |
peroxiredoxin 2 |
| Synonyms gene: |
TDPX1 |
| Synonyms: |
PRP NKEFB TSA PRXII PRX2 MGC4104 |
| Synonyms name: |
thioredoxin-dependent peroxide reductase 1 thiol-specific antioxidant 1 natural killer-enhancing factor B thioredoxin peroxidase 1 torin |
| Locus: |
19p13, 13 |
| Discovery year: |
1995-07-06 |
| Entrez gene record: |
7001 |
| Pubmed identfication: |
7607688 |
| RefSeq identity: |
NM_005809 |
| Classification: |
Peroxiredoxins |
| Havana BLAST/BLAT: |
OTTHUMG00000134285 |