| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DPYD |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the DPYD antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This DPYD antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q12882 |
| Purity: |
Antigen affinity |
| Description: |
By cDNA microarray, By fluorescence in situ hybridization, The activity of DPYD in peripheral blood mononuclear cells was intermediate between that observed in monocytes and lymphocytes, The highest level of DPYD was found in monocytes followed by that in lymphocytes, The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism, The structure of the gene contains 23 exons spanning about 950 kb, Using somatic cell hybrid strategies, Western blot analysis, also called DPD, and luciferase reporter assay, and platelets, granulocytes, is an enzyme that in humans is encoded by the DPYD gene, the gene is mapped to 1p22, the gene was mapped to the centromeric region of chromosome 1 between 1p22 and 1q21, the transcription factor LSF was identified as a positive regulator of DPYD, whereas no significant activity could be detected in erythrocytes, Dihydropyrimidine Dehydrogenase |
| Immunogen: |
Amino acids 33-52 (AKKLDKKHWKRNPDKNCFNC-human) were used as the immunogen for this DPYD antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DPYD antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DPYD |
| Short name: |
DPYD Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DPYD (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3012 |
| Gene: |
DPYD |
More about : DPYD |
| Long gene name: |
dihydropyrimidine dehydrogenase |
| Synonyms: |
DPD |
| Locus: |
1p21, 3 |
| Discovery year: |
1994-07-07 |
| GenBank acession: |
U20938 |
| Entrez gene record: |
1806 |
| Pubmed identfication: |
7713523 |
| RefSeq identity: |
NM_000110 |
| Havana BLAST/BLAT: |
OTTHUMG00000039683 |
| Locus Specific Databases: |
UMD Locus Specific Databases LRG_722 |