| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TFF1 (Estrogen Inducible Protein) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the TFF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TFF1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q08423 |
| Purity: |
Antigen affinity |
| Description: |
Concentrations and relative amounts of the protein in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls, It is found that the protein in normal human urine inhibited the growth of calcium oxalate crystals, Members of the trefoil family are characterized by having at least one copy of the trefoil motif, Their functions are not defined, They are stable secretory proteins expressed in gastrointestinal mucosa, This gene, This gene and two other related trefoil family member genes are found in a cluster on chromosome 21, Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, a 40-amino acid domain that contains three conserved disulfides, also known as Estrogen inducible factor pS2, and affect healing of the epithelium, and inhibition was dose dependent and inhibited by TFF1 antisera, but they may protect the mucosa from insults, has also been studied because of its expression in human tumors, is a protein that in humans is encoded by the TFF1 gene, particularly by antisera directed to the TFF1 C terminus, stabilize the mucus layer, which is expressed in the gastric mucosa, Trefoil factor 1 |
| Immunogen: |
An amino acid sequence from the middle region of mouse Estrogen Inducible Protein pS2 (CCFDDSVRGFPWCF) was used as the immunogen for this TFF1 antibody (100% rat homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TFF1 antibody can be stored for up to one month at 4oC, After reconstitution |
| French translation: |
anticorps |
| Gene target: |
TFF1 (Estrogen Protein) |
| Short name: |
TFF1 antibody (Estrogen Protein) |
| Alternative name: |
TFF1 (Antibody to) (Estrogen Inducible Protein) |
| Alternative technique: |
antibodies |
| Identity: |
11755 |
| Gene: |
TFF1 |
More about : TFF1 |
| Long gene name: |
trefoil factor 1 |
| Synonyms gene: |
BCEI |
| Synonyms gene name: |
breast cancer, estrogen-inducible sequence expressed in |
| Synonyms: |
D21S21 HPS2 pS2 pNR-2 HP1, A |
| Locus: |
21q22, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
BC032811 |
| Entrez gene record: |
7031 |
| Pubmed identfication: |
9043862 |
| RefSeq identity: |
NM_003225 |
| Havana BLAST/BLAT: |
OTTHUMG00000086799 |