| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
EP1 subtype, PGE Receptor |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the PGE Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This PGE Receptor antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P34995 |
| Purity: |
Antigen affinity |
| Description: |
Gq proteins mediate this receptor's activity, Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure, Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin, The PTGER1 gene is mapped to chromosome 19p13, The protein encoded by this gene is a member of the G protein-coupled receptor family, This protein is one of four receptors identified for prostaglandin E (PGE), Through a phosphatidylinositol-calcium second messenger system, 1, Prostaglandin E Receptor 1 is a 402 amino acid protein with a predicted molecular mass of 44KD and has the seven transmembrane-spanning domains common to all G protein-coupled receptors |
| Immunogen: |
An amino acid sequence from the C-terminus of human PGE Receptor EP1 subtype (AWEASSLRSSRHSGLSHF) was used as the immunogen for this PGE Receptor antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PGE Receptor antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PGE Receptor EP1 subtype |
| Short name: |
EP1 subtype, PGE Receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
EP1 subtype, PGE Receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9593 |
| Gene: |
PTGER1 |
More about : PTGER1 |
| Long gene name: |
prostaglandin E receptor 1 |
| Synonyms gene name: |
42kD prostaglandin E receptor 1 (subtype EP1), 42kDa , prostaglandin E receptor 1 (subtype EP1) |
| Synonyms: |
EP1 |
| Locus: |
19p13, 1 |
| Discovery year: |
1994-07-29 |
| Pubmed identfication: |
8253813 |
| Classification: |
Prostaglandin (prostanoid) receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000039610 |