| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
DAPK2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the DAPK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This DAPK2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UIK4 |
| Purity: |
Antigen affinity |
| Description: |
It uses multiple polyadenylation sites, Overexpression of this gene was shown to induce cell apoptosis, The DAPK2 mRNA may undergo alternative splicing to produce a DAPK3-like encoding transcript, This gene encodes a protein that belongs to the serine/threonine protein kinase family, This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1(DAPK1), a positive regulator of programmed cell death, also called DAP kinase related protein 1 (DRP-1), is an enzyme that in humans is encoded by the DAPK2 gene, Death-associated protein kinase 2 |
| Immunogen: |
An amino acid sequence from the C-terminus of human DAPK2 (DNQQAMVRRESVVNLENFRK) was used as the immunogen for this DAPK2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DAPK2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
DAPK2 |
| Short name: |
DAPK2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
death-associated protein kinase 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, DAPK2 and IDBG-16095 and ENSG00000035664 and 23604, DAPK2 and IDBG-646506 and ENSBTAG00000011820 and 529131, DRP-1 and DRP1, Dapk2 and IDBG-178934 and ENSMUSG00000032380 and 13143, this GO :0003824 and catalytic activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004683 and calmodulin-dependent protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0016772 and transferase activity, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004683 : calmodulin-dependent protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005516 : calmodulin binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004683 : calmodulin-dependent protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005516 : calmodulin binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0042802 : identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042802 : identical protein binding, transferring phosphorus-containing groups and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0034423 and autophagic vacuole lumen and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043276 and anoikis and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :2001242 and regulation of intrinsic apoptotic signaling pathway and biological process, death-associated protein kinase 2 |
| Identity: |
2675 |
| Gene: |
DAPK2 |
More about : DAPK2 |
| Long gene name: |
death associated protein kinase 2 |
| Synonyms: |
DRP-1 MGC119312 |
| Locus: |
15q22, 31 |
| Discovery year: |
1999-10-19 |
| GenBank acession: |
AB018001 |
| Entrez gene record: |
23604 |
| Pubmed identfication: |
10376525 |
| RefSeq identity: |
NM_014326 |
| Classification: |
Death associated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000132947 |