| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cdk5 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Cdk5 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Cdk5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q00535 |
| Purity: |
Antigen affinity |
| Description: |
Cdk5 expression is in all human tissues and cell lines tested, Cdk5 must associate with its regulatory subunit, Cyclin-dependent kinase 5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau, It can phosphorylate DARPP32 at threonine-75, It is required for proper development of the mammalian central nervous system, The p34(CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle, The the gene is mapped to chromosome 7q36, To be activated, converting it into an inhibitor of PKA, is also know as PSSALRE, p35(CDK5R1), Cyclin-Dependent Kinase 5 |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human Cdk5 (QRISAEEALQHPYFSDFCPP) was used as the immunogen for this Cdk5 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cdk5 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cdk5 |
| Short name: |
Cdk5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
cyclin-dependent kinase 5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1774 |
| Gene: |
CDK5 |
More about : CDK5 |
| Long gene name: |
cyclin dependent kinase 5 |
| Synonyms: |
PSSALRE |
| Locus: |
7q36, 1 |
| Discovery year: |
1993-07-28 |
| GenBank acession: |
X66364 |
| Entrez gene record: |
1020 |
| Pubmed identfication: |
8275715 1639063 |
| Classification: |
Cyclin dependent kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000158414 |