| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CD147 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the CD147 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CD147 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P35613 |
| Purity: |
Antigen affinity |
| Description: |
As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, CD147 also regulates several distinct functions, CD147 has been shown to be an essential receptor on red blood cells for the malaria parasite, It is a member of the immunoglobulin superfamily, It is a type I integral membrane receptor that has many ligands, It is expressed by many cell types, It is though also to play a role in intercellular recognition, The gene contains 8 exons and spans 10, This protein is a determinant for the Ok blood group system, also known as Emmprin(BSG) or cluster of differentiation 147 is a protein that in humans is encoded by the Emmprin gene, and development, differentiation, endothelial cells and leukocytes, expression of the monocarboxylate transporter and the responsiveness of lymphocytes, extracellular matrix metalloproteinase inducer, including epithelial cells, including the cyclophilin(CyP) proteins Cyp-A and CyP-B and certain integrins, such as spermatogenesis, with a structure related to the putative primordial form of the family, 8 kb, Emmprin |
| Immunogen: |
An amino acid sequence from the middle region of human CD147 (QKTEFKVDSDDQWGEYSC) was used as the immunogen for this CD147 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD147 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CD147 |
| Short name: |
CD147 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD147 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1116 |
| Gene: |
BSG |
More about : BSG |
| Long gene name: |
basigin (Ok blood group) |
| Synonyms gene: |
OK |
| Synonyms gene name: |
basigin |
| Synonyms: |
EMMPRIN CD147 |
| Synonyms name: |
Ok blood group |
| Locus: |
19p13, 3 |
| Discovery year: |
1993-10-25 |
| GenBank acession: |
L10240 |
| Entrez gene record: |
682 |
| Pubmed identfication: |
8404035 7812975 |
| RefSeq identity: |
NM_001728 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing CD molecules Blood group antigens |
| Havana BLAST/BLAT: |
OTTHUMG00000177718 |
| Locus Specific Databases: |
Blood Group Antigen Mutation Database LRG_816 |