| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FGF19 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, IHC (Paraffin): 1-2ug/ml, Western blot: 0 |
| Notes: |
Titration of the FGF19 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This FGF19 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O95750 |
| Purity: |
Antigen affinity |
| Description: |
Expression of this gene was detected only in fetal but not adult brain tissue, FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis, Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development, The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family, The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, The gene is mapped to 11q13, The protein encoded by this gene is a member of the fibroblast growth factor(FGF) family, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity, instead, is a protein that in humans is encoded by the FGF19 gene, 3, Fibroblast growth factor 19 |
| Immunogen: |
An amino acid sequence from the middle region of human FGF19 (EEIRPDGYNVYRSEKHR) was used as the immunogen for this FGF19 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FGF19 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FGF19 |
| Short name: |
FGF19 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
fibroblast growth factor 19 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, FGF19 and IDBG-61980 and ENSG00000162344 and 9965, FGF19 and IDBG-645026 and ENSBTAG00000017285 and 521475, Fgf15 and IDBG-212954 and ENSMUSG00000031073 and 14170, growth factor activity, this GO :0001755 and neural crest cell migration and biological process this GO :0005104 and fibroblast growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070858 and negative regulation of bile acid biosynthetic process and biological process, this GO :0005104 : fibroblast growth factor receptor binding, this GO :0005104 : fibroblast growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, fibroblast growth factor 19 |
| Identity: |
3675 |
| Gene: |
FGF19 |
More about : FGF19 |
| Long gene name: |
fibroblast growth factor 19 |
| Locus: |
11q13, 3 |
| Discovery year: |
1999-05-06 |
| GenBank acession: |
AB018122 |
| Entrez gene record: |
9965 |
| Pubmed identfication: |
9931477 10525310 |
| RefSeq identity: |
NM_005117 |
| Havana BLAST/BLAT: |
OTTHUMG00000167886 |