| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cdk4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Cdk4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Cdk4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P30285 |
| Purity: |
Antigen affinity |
| Description: |
CDK4 expression and activity are required for cytokine responsiveness in T cells, CDK4 is inhibited by p16, CDK4 is mapped to 12q14, Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle, The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase, also known as cyclin-dependent kinase inhibitor-2, Cyclin-dependent kinase-4(CDK4) is a protein-serine kinase involved in the cell cycle |
| Immunogen: |
An amino acid sequence from the C-terminus of mouse Cdk4 (RISAFRALQHSYLHKEESDAE) was used as the immunogen for this Cdk4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cdk4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cdk4 |
| Short name: |
Cdk4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
cyclin-dependent kinase 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1773 |
| Gene: |
CDK4 |
More about : CDK4 |
| Long gene name: |
cyclin dependent kinase 4 |
| Synonyms: |
PSK-J3 |
| Locus: |
12q14, 1 |
| Discovery year: |
1993-07-28 |
| GenBank acession: |
M14505 |
| Entrez gene record: |
1019 |
| Pubmed identfication: |
8275715 |
| RefSeq identity: |
NM_000075 |
| Classification: |
Cyclin dependent kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000170382 |
| Locus Specific Databases: |
LRG_490 |