| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CX3CL1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the CX3CL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CX3CL1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P78423 |
| Purity: |
Antigen affinity |
| Description: |
601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine, Being the large protein, Imai et al, It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice), It is said to be the only known member of the CX3C chemokine family, Its gene is mapped to the long arm of chromosome 8, it has got 373 amino acids, (1997) identified a 7-transmembrane high-affinity receptor(CX3CR1, Chemokine(C-X3-C motif) ligand 1 is a large cytokine protein |
| Immunogen: |
An amino acid sequence from the N-terminus of human CX3CL1 (HYQQNQASCGKRAII) was used as the immunogen for this CX3CL1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CX3CL1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CX3CL1 |
| Short name: |
CX3CL1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-X3-C motif) ligand 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ABCD-3 and C3Xkine and CXC3 and CXC3C and fractalkine and neurotactin and NTN and NTT and SCYD1, CX3CL1 and IDBG-33205 and ENSG00000006210 and 6376, CX3CL1 and IDBG-632469 and ENSBTAG00000024869 and, Cx3cl1 and IDBG-182616 and ENSMUSG00000031778 and 20312, Extracellular, chemokine activity, this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006952 and defense response and biological process this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0008009 and chemokine activity and molecular function this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0030595 and leukocyte chemotaxis and biological process this GO :0032914 and positive regulation of transforming growth factor beta1 production and biological process this GO :0042060 and wound healing and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048246 and macrophage chemotaxis and biological process this GO :0048247 and lymphocyte chemotaxis and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050902 and leukocyte adhesive activation and biological process this GO :0051041 and positive regulation of calcium-independent cell-cell adhesion and biological process this GO :0060055 and angiogenesis involved in wound healing and biological process this GO :0060326 and cell chemotaxis and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008009 : chemokine activity, this GO :0005515 : protein binding, this GO :0008009 : chemokine activity, chemokine (C-X3-C motif) ligand 1 |
| Identity: |
10647 |
| Gene: |
CX3CL1 |
More about : CX3CL1 |
| Long gene name: |
C-X3-C motif chemokine ligand 1 |
| Synonyms gene: |
SCYD1 |
| Synonyms gene name: |
member 1 (fractalkine, neurotactin) chemokine (C-X3-C motif) ligand 1 , small inducible cytokine subfamily D (Cys-X3-Cys) |
| Synonyms: |
NTN C3Xkine ABCD-3 CXC3C CXC3 fractalkine neurotactin |
| Locus: |
16q21 |
| Discovery year: |
1997-08-22 |
| GenBank acession: |
U84487 |
| Entrez gene record: |
6376 |
| Pubmed identfication: |
9177350 9024663 |
| RefSeq identity: |
NM_002996 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000133469 |