| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
P-Cadherin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the P-Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This P-Cadherin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P22223 |
| Purity: |
Antigen affinity |
| Description: |
In addition, Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy, P-Cadherin is a protein that in humans is encoded by the CDH3 gene, The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer, a transmembrane region and a highly conserved cytoplasmic tail, aberrant expression of this protein is observed in cervical adenocarcinomas, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion, such as CDH3, Cadherins |
| Immunogen: |
Amino acids 612-626 (QDTYDVHLSLSDHGN-human) were used as the immunogen for this P-Cadherin antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the P-Cadherin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
P-Cadherin |
| Short name: |
P-Cadherin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
P-Cadherin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1762 |
| Gene: |
CDH3 |
More about : CDH3 |
| Long gene name: |
cadherin 3 |
| Synonyms gene name: |
P-cadherin (placental) , P-cadherin (placental) cadherin 3, cadherin 3, type 1 |
| Synonyms: |
CDHP PCAD |
| Locus: |
16q22, 1 |
| Discovery year: |
1992-07-10 |
| GenBank acession: |
X63629 |
| Entrez gene record: |
1001 |
| Pubmed identfication: |
1427864 |
| RefSeq identity: |
NM_001793 |
| Classification: |
Type I classical cadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000137560 |
| Locus Specific Databases: |
Mutations of the P-Cadherin Gene |