| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IL-8 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the IL-8 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This IL-8 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P10145 |
| Purity: |
Antigen affinity |
| Description: |
2001), IL-8 is believed to play a role in the pathogenesis of bronchiolitis, In humans, Interleukin-8(IL8) is a member of the CXC chemokine family(Hull et al, It is also synthesized by endothelial cells, The genes for IL8 have been co-localized on a 335-kb genomic fragment, This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q, a common respiratory tract disease caused by viral infection, the Weibel-Palade bodies, the interleukin-8 protein is encoded by the IL8 gene, which store IL-8 in their storage vesicles, Interleukin-8(IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells |
| Immunogen: |
An amino acid sequence from the C-terminus of human IL8 (CLDPKENWVQRVVEKFLKR) was used as the immunogen for this IL-8 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IL-8 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IL-8 |
| Short name: |
IL-8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Interleukin-8 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6025 |
| Gene: |
CXCL8 |
More about : CXCL8 |
| Long gene name: |
C-X-C motif chemokine ligand 8 |
| Synonyms gene: |
IL8 |
| Synonyms gene name: |
interleukin 8 chemokine (C-X-C motif) ligand 8 |
| Synonyms: |
SCYB8 LUCT LECT MDNCF TSG-1 IL-8 NAP-1 3-10C MONAP AMCF-I LYNAP NAF b-ENAP GCP-1 K60 GCP1 NAP1 |
| Synonyms name: |
neutrophil-activating peptide 1 granulocyte chemotactic protein 1 monocyte-derived neutrophil chemotactic factor lung giant cell carcinoma-derived chemotactic protein tumor necrosis factor-induced gene 1 monocyte-derived neutrophil-activating peptide lymphocyte derived neutrophil activating peptide beta endothelial cell-derived neutrophil activating peptide alveolar macrophage chemotactic factor I |
| Locus: |
4q13, 3 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
Y00787 |
| Entrez gene record: |
3576 |
| Pubmed identfication: |
1427896 11178128 |
| RefSeq identity: |
NM_000584 |
| Classification: |
Endogenous ligands Chemokine ligands Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000151316 |