| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FAF1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the FAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This FAF1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UNN5 |
| Purity: |
Antigen affinity |
| Description: |
FAF1 is involved in negative regulation of NF-kappaB activation, In addition to the previously known function as a component of the Fas death-inducing signaling complex, NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction, Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines, and heart as 2, hFAF1 was expressed abundantly in testis, i, skeletal muscle, 8 kb mRNA, Fas-associated factor-1(FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis, e |
| Immunogen: |
mouse and rat), An amino acid sequence from the N-terminus of human FAF1 (MASNMDREMILADFQACTGIEN) was used as the immunogen for this FAF1 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FAF1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FAF1 |
| Short name: |
FAF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 6) (TNFRSF6) associated factor 1 (Antibody to), Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
FAF1 and IDBG-639656 and ENSBTAG00000014482 and 531770, FAF1 and IDBG-98407 and ENSG00000185104 and 11124, Faf1 and IDBG-174694 and ENSMUSG00000010517 and 14084, NF-kappaB binding, hFAF1 and HFAF1s and UBXD12 and UBXN3A, nuclei, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007253 and cytoplasmic sequestering of NF-kappaB and biological process this GO :0008219 and cell death and biological process this GO :0019887 and protein kinase regulator activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0030155 and regulation of cell adhesion and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0031265 and CD95 death-inducing signaling complex and cellular component this GO :0031334 and positive regulation of protein complex assembly and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0034098 and Cdc48p-Npl4p-Ufd1p AAA ATPase complex and cellular component this GO :0042176 and regulation of protein catabolic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0045859 and regulation of protein kinase activity and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051059 and NF-kappaB binding and molecular function this GO :1902043 and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0019887 : protein kinase regulator activity and also this GO :0019901 : protein kinase binding and also this GO :0019904 : protein domain specific binding and also this GO :0031072 : heat shock protein binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0043130 : ubiquitin binding and also this GO :0051059 : NF-kappaB binding, this GO :0019887 : protein kinase regulator activity, this GO :0019901 : protein kinase binding, this GO :0019904 : protein domain specific binding, this GO :0031072 : heat shock protein binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0043130 : ubiquitin binding, this GO :0051059 : NF-kappaB binding, Fas (TNFRSF6) associated factor 1 |
| Identity: |
3578 |
| Gene: |
FAF1 |
More about : FAF1 |
| Long gene name: |
Fas associated factor 1 |
| Synonyms gene name: |
Fas (TNFRSF6) associated factor 1 |
| Synonyms: |
CGI-03 hFAF1 HFAF1s UBXD12 UBXN3A |
| Synonyms name: |
TNFRSF6-associated factor 1 UBX domain protein 3A |
| Locus: |
1p32, 3 |
| Discovery year: |
1999-12-10 |
| GenBank acession: |
AF132938 |
| Entrez gene record: |
11124 |
| Pubmed identfication: |
10462485 |
| RefSeq identity: |
NM_007051 |
| Classification: |
UBX domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000007930 |