| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Hex |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Hex antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Hex antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q03014 |
| Purity: |
Antigen affinity |
| Description: |
And using somatic cell hybrid analysis, D'Elia et al, Homeobox genes are involved in neoplastic transformation of both epithelial and hemopoietic tissues, Homeobox genes are members of a family of transcription factors that regulate tissue development in many different organisms, Hromas et al, The divergent homeobox gene HEX is expressed in the anterior visceral endoderm during early mouse development and in some adult tissues of endodermal origin, including liver and thyroid, they mapped the HHEX gene to chromosome 10, where the HOX11 gene is located, 's findings suggested that regulation of HEX entry in the nucleus of thyrocytes may represent a critical step during human thyroid tumorigenesis, (1993) set out to identify homeobox genes that might play a role in hematopoiesis, Hematopoietically-expressed homeobox protein HHEX is a protein that in humans is encoded by the HHEX gene |
| Immunogen: |
An amino acid sequence from the N-terminus of human Hex (QPAHPTPFYIEDILGR) was used as the immunogen for this Hex antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Hex antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Hex |
| Short name: |
Hex Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Hex (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4901 |
| Gene: |
HHEX |
More about : HHEX |
| Long gene name: |
hematopoietically expressed homeobox |
| Synonyms gene: |
PRHX |
| Synonyms: |
HEX HOX11L-PEN |
| Locus: |
10q23, 33 |
| Discovery year: |
1998-08-04 |
| GenBank acession: |
Z21533 |
| Entrez gene record: |
3087 |
| Pubmed identfication: |
8096636 8103988 |
| Classification: |
NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000018762 |