| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PP2Ac |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Variations in secondary/substrate sensitivities and test protocols may require the PP2Ac antibody to be titrated for optimal performance |
| Intented use: |
This PP2Ac antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P67775 |
| Purity: |
Antigen affinity |
| Description: |
Furthermore, It is predicted to be important for phosphatase enzymatic activity, Methylation of the C-terminal leucine residue (Leu309) of PPP2CA is known to regulate catalytic activity in vitro, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases, The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide |
| Immunogen: |
mouse and rat), An amino acid sequence from the N-terminus of human PPP2CA (FTKELDQWIEQLNEC) was used as the immunogen for this PP2Ac antibody (100% homologous in human |
| Storage: |
After reconstitution, Avoid repeated freeze/thaws, Celcius or lower, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, The lyophilized PP2Ac antibody can be stored at 4oC to -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PP2Ac |
| Short name: |
PP2Ac Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PP2Ac (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9299 |
| Gene: |
PPP2CA |
More about : PPP2CA |
| Long gene name: |
protein phosphatase 2 catalytic subunit alpha |
| Synonyms gene name: |
alpha isoform protein phosphatase 2, alpha isozyme , catalytic subunit, catalytic subunit, protein phosphatase 2 (formerly 2A) |
| Synonyms: |
PP2Calpha PP2AC |
| Synonyms name: |
alpha isoform , protein phosphatase 2A catalytic subunit |
| Locus: |
5q31, 1 |
| Discovery year: |
1992-11-10 |
| Entrez gene record: |
5515 |
| Pubmed identfication: |
8383590 |
| RefSeq identity: |
NM_002715 |
| Classification: |
STRIPAK complex Protein phosphatase catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000129119 |