| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cx43 Connexin 43 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the Cx43 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Cx43 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P17302 |
| Purity: |
Antigen affinity |
| Description: |
Connexin 43, Cx43 also plays a critical role in the physiology of hearing, alpha, also called GAP Junction Protein, is a member of the connexin gene family and is abundantly expressed in the heart and liver, is targeted by several protein kinases that regulate myocardial cell-cell coupling, presumably by participating in the recycling of potassium to the cochlear endolymph, the major protein of gap junctions in the heart, Connexin 43 (Cx43) |
| Immunogen: |
Amino acids 351-367 (HELQPLAIVDQRPSSRA-human) were used as the immunogen for this Cx43 antibody (100% conserved in mouse and rat) |
| Storage: |
After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, The lyophilized Cx43 antibody can be stored at 4oC to -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cx43 Connexin 43 |
| Short name: |
Cx43 Antibody Connexin 43 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cx43 (Antibody to) Connexin 43 |
| Alternative technique: |
antibodies |
| Identity: |
4274 |
| Gene: |
GJA1 |
More about : GJA1 |
| Long gene name: |
gap junction protein alpha 1 |
| Synonyms gene: |
ODDD GJAL |
| Synonyms gene name: |
43kDa , 43kDa (connexin 43) gap junction protein, alpha 1, alpha 1, alpha-like gap junction protein, gap junction protein |
| Synonyms: |
CX43 ODD ODOD SDTY3 |
| Synonyms name: |
oculodentodigital dysplasia (syndactyly type III) connexin 43 |
| Locus: |
6q22, 31 |
| Discovery year: |
1990-08-03 |
| GenBank acession: |
BC026329 |
| Entrez gene record: |
2697 |
| Pubmed identfication: |
10331943 1646158 |
| RefSeq identity: |
NM_000165 |
| Classification: |
Gap junction proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000015479 |
| Locus Specific Databases: |
Hereditary Hearing Loss Homepage |