| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AQP1 Aquaporin 1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the AQP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This AQP1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P29972 |
| Purity: |
Antigen affinity |
| Description: |
It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient, Aquaporin 1 is a 28-kD integral protein though at first to be a breakdown product of the Rh polypeptide but was later shown to be a unique molecule that is abundant in erythrocytes and renal tubules as well as being expressed by the choroid plexus and various other tissues |
| Immunogen: |
An amino acid sequence from the C-terminus of human Aquaporin 1 (EEYDLDADDINSRVEMKPK) was used as the immunogen for this AQP1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the AQP1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AQP1 Aquaporin 1 |
| Short name: |
AQP1 Antibody Aquaporin 1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Uncharacterized protein (Antibody to) Aquaporin 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AQP1 and IDBG-407682 and ENSG00000250424 and, Plasma membranes, this GO :0005215 and transporter activity and molecular function this GO :0006810 and transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component, this GO :0005215 : transporter activity, this GO :0005215 : transporter activity, transporter activity, Uncharacterized protein |
| Identity: |
633 |
| Gene: |
AQP1 |
More about : AQP1 |
| Long gene name: |
aquaporin 1 (Colton blood group) |
| Synonyms gene: |
CO |
| Synonyms gene name: |
28kDa, 28kDa) aquaporin 1 (channel-forming integral protein, CO blood group) aquaporin 1 , Colton blood group aquaporin 1 (channel-forming integral protein |
| Synonyms: |
CHIP28 |
| Locus: |
7p14, 3 |
| Discovery year: |
1993-07-09 |
| GenBank acession: |
M77829 |
| Entrez gene record: |
358 |
| Pubmed identfication: |
1722319 3166547 |
| RefSeq identity: |
NM_000385 |
| Classification: |
Aquaporins Blood group antigens |
| Havana BLAST/BLAT: |
OTTHUMG00000023944 |
| Locus Specific Databases: |
Blood Group Antigen Mutation Database LRG_808 |