| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HGF |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the HGF antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This HGF antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
15234 |
| Purity: |
Antigen affinity |
| Description: |
HGF also serves as a paracrine mediator to control placental development and growth, HGF can regulate cell growth, HGF was identified as one of the liver sinusoidal endothelial cell-derived paracrine mediators promoting hepatocyte growth, It has been shown to have a major role in embryonic organ development, It is secreted by mesenchymal cells and targets and acts primarily uponepithelial cells and endothelial cells, This gene is mapped to 7q21, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, but also acts on haemopoietic progenitor cells, cell motility, in adult organ regeneration and in wound healing, motility and morphogenic factor, specifically in myogenesis, 11, Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth |
| Immunogen: |
An amino acid sequence from the N-terminus of mouse HGF (QKKRRNTLHEFKKSAKTTLTKEDPLLKIKTKK) was used as the immunogen for this HGF antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HGF antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HGF |
| Short name: |
HGF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
scatter factor) (Antibody to), hepatocyte growth factor (hepapoietin A |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DFNB39 and F-TCF and HGFB and HPTA and SF, Extracellular, HGF and IDBG-24150 and ENSG00000019991 and 3082, HGF and IDBG-631194 and ENSBTAG00000017664 and 282879, Hgf and IDBG-136449 and ENSMUSG00000028864 and 15234, protein heterodimerization activity, scatter factor), this GO :0000187 and activation of MAPK activity and biological process this GO :0000902 and cell morphogenesis and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001889 and liver development and biological process this GO :0002576 and platelet degranulation and biological process this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006508 and proteolysis and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007596 and blood coagulation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0030212 and hyaluronan metabolic process and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031100 and organ regeneration and biological process this GO :0031643 and positive regulation of myelination and biological process this GO :0035729 and cellular response to hepatocyte growth factor stimulus and biological process this GO :0042056 and chemoattractant activity and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048012 and hepatocyte growth factor receptor signaling pathway and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050918 and positive chemotaxis and biological process this GO :0051450 and myoblast proliferation and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0060665 and regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling and biological process this GO :0070572 and positive regulation of neuron projection regeneration and biological process this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process this GO :1901299 and negative regulation of hydrogen peroxide-mediated programmed cell death and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000573 and positive regulation of DNA biosynthetic process and biological process, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004252 : serine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0042056 : chemoattractant activity and also this GO :0042802 : identical protein binding and also this GO :0046982 : protein heterodimerization activity, this GO :0004252 : serine-type endopeptidase activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0042056 : chemoattractant activity, this GO :0042802 : identical protein binding, this GO :0046982 : protein heterodimerization activity, hepatocyte growth factor (hepapoietin A |
| Identity: |
11187 |
| Gene: |
SOS1 |
More about : SOS1 |
| Long gene name: |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
| Synonyms gene: |
GINGF |
| Synonyms gene name: |
1 son of sevenless homolog 1 (Drosophila) , gingival fibromatosis, hereditary |
| Synonyms: |
HGF GF1 |
| Locus: |
2p22, 1 |
| Discovery year: |
1993-10-27 |
| GenBank acession: |
L13857 |
| Entrez gene record: |
6654 |
| Pubmed identfication: |
8276400 10995566 |
| RefSeq identity: |
NM_005633 |
| Classification: |
Rho guanine nucleotide exchange factors Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000102109 |
| Locus Specific Databases: |
LRG_754 |