| Gene info: |
Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5), Expression of vinculin were shown to be affected by the level of actin expression (2, Three structural vinculin domains include an amino-terminal head, Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, a short flexible proline-rich region and a carboxy-terminal tail (2), suggesting a possible role in metastatic growth (4), 3), Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1) |
| Gene names: |
CMH15, MVCL, Metavinculin, CMD1W |
| Antibodie's label: |
unlabelled serum |
| Purity: |
Vinculin antibody is purified via Protein A prification |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Immunoglobulin: |
IgG |
| Spicific to: |
At least three isoforms of Vinculin are known to exist, mouse, rabbit and chicken reactive, rat, Vinculin antibody is human |
| Antigen: |
Vinculin antibody was made against a 23 amino acid peptide near the amino terminus of human Vinculin |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
5 - 1 ug/ml, Vinculin antibody can be used for detection of Vinculin by Western blot at 0 |
| Suspention, pH, azide: |
02% sodium azide, Vinculin Antibody is supplied in PBS containing 0 |
| Keep at: |
stable for up to one year, Vinculin antibody can be stored at 4 grades C for three months and -20 grades C |
| Works with: |
Chicken, Mouse, Rabbit, Rat, Human |
| Omim nr: |
4507877 |
| Ncbi nr: |
NP_003364 |
| KDa: |
Predicted: 117 kDa Observed: 120 kDa |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
7414 |
| GENE symbol: |
VCL |
| Antigene name: |
vinculin |
| Source: |
homo sapiens |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
Vinculin [8B5] |
| Short name: |
anti-Vinculin Antibody [8B5] |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-Vinculin (Antibody to) [8B5] |
| Alternative technique: |
antibodies |