| Gene info: |
The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes, Together with other UPR transcription factors such as ATF6, Upon sensing unfolded proteins, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA, XBP-1 Monoclonal Antibody: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER) |
| Gene names: |
TREB5, XBP-1, XBP-1 Antibody [9B7E5] : XBP2 |
| Antibodie's label: |
unlabelled serum |
| Purity: |
XBP-1 Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
9B7E5 |
| Antigen: |
Mouse monoclonal XBP-1 antibody was made against recombinant protein corresponding to amino acids 2 to 160 of human XBP-1 |
| Immuno application: |
Western Blot, immuno fluorescence, immuno-cyto-chemistry, ELISA |
| Antibody advice: |
Antibody can also be used for immunocytochemistry starting at 2 ug/mL, For immunofluorescence start at 4 ug/mL, XBP-1 antibody can be used for the detection of XBP-1 by Western blot at 1 ug/mL |
| Suspention, pH, azide: |
02% sodium azide, XBP-1 Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at: |
stable for one year, XBP-1 monoclonal antibody can be stored at -20 grades C |
| Works with: |
Mouse, Rat, Human |
| Omim nr: |
18148382 |
| Ncbi nr: |
BAB82982 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
7494 |
| GENE symbol: |
XBP1 |
| Antigene name: |
X-box binding protein 1 |
| Source: |
Homo sapiens |
| Protein nr: |
P17861 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
XBP-1 [9B7E5] |
| Short name: |
anti-XBP-1 Antibody [9B7E5] |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-XBP-1 (Antibody to) [9B7E5] |
| Alternative technique: |
antibodies |