| Gene info: |
Caspase and CAD independent DNA fragmentation also exists, Caspase-activated deoxyribonuclease (CAD), EndoG also cleaves DNA in vitro, EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis, Recent studies demonstrated that another nuclease, The activities of caspase and nuclease are involved in the DNA fragmentation, The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in <, also termed DNA fragmentation factor (DFF40), and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45, elegans<, endonuclease G (EndoG), is one such nuclease, is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD, /i>, C, EndoG Monoclonal Antibody: The fragmentation of nuclear DNA is a hallmark of apoptotic cell death, i> |
| Gene names: |
EndoG Antibody [7F2D7] : Endo G |
| Antibodie's label: |
unlabelled serum |
| Purity: |
EndoG Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
7F2D7 |
| Immunoglobulin: |
IgG1 |
| Antigen: |
Recombinant protein corresponding to amino acids 51 - 140 of human EndoG |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
EndoG monoclonal antibody can be used for detection of EndoG by Western blot at 5 - 10 ug/mL |
| Suspention, pH, azide: |
02% sodium azide, EndoG Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at: |
stable for one year, EndoG monoclonal antibody can be stored at -20 grades C |
| Works with: |
Mouse, Rat, Human |
| Omim nr: |
24638471 |
| Ncbi nr: |
Q14249 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
2021 |
| GENE symbol: |
ENDOG |
| Antigene name: |
endonuclease G |
| Source: |
Homo sapiens |
| Protein nr: |
Q14249 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
EndoG [7F2D7] |
| Short name: |
anti-EndoG Antibody [7F2D7] |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-endonuclease G (Antibody to) [7F2D7] |
| Alternative technique: |
antibodies |