| Category: |
Antibody |
| Concentration: |
05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ATG4B |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 4-6ug/ml |
| Notes: |
ATG4B antibody titration may be required for optimal results, Provided assay concentrations are suggestions only |
| Added buffer: |
pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use: |
This ATG4B antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
23192 |
| Purity: |
Purified by protein A Affinity Chromatography |
| Description: |
ATG4B is a regulator of autophagasome maturation, ATG4B regulates LC3-II availability by modulating LC3-I lipidation, The &lsquo, The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes, The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled, Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components, autophagy-related gene&rsquo |
| Immunogen: |
A recombinant protein fragment from the N-terminal region of ATG4B was used as the immunogen for this antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ATFG4B antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ATG4B |
| Short name: |
ATG4B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ATG4B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20790 |
| Gene: |
ATG4B |
More about : ATG4B |
| Long gene name: |
autophagy related 4B cysteine peptidase |
| Synonyms gene: |
APG4B |
| Synonyms gene name: |
APG4 autophagy 4 homolog B (S, cerevisiae) ATG4 autophagy related 4 homolog B (S, cerevisiae) autophagy related 4B, cysteine peptidase |
| Synonyms: |
Apg4B KIAA0943 DKFZp586D1822 AUTL1 |
| Locus: |
2q37, 3 |
| Discovery year: |
2004-03-23 |
| GenBank acession: |
AB023160 |
| Entrez gene record: |
23192 |
| Pubmed identfication: |
12446702 |
| RefSeq identity: |
NM_013325 |
| Classification: |
Autophagy related |
| Havana BLAST/BLAT: |
OTTHUMG00000151514 |