| Also known as: |
Fas Ligand (FITC) |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
H11 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, N/A |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human Fas Ligand |
| Purification method: |
95% as determined by SDS-Page, > |
| Form/Appearance: |
03% NaN3, Supplied in PBS buffer with 0 |
| Storage and shipping: |
Do NOT freeze the antibody, Temperature variations in the range 1°, keep the antibody at +4°, C, C are tolerable, C to 9°, For optimal storage conditions |
| Tested applications:: |
Immunohistochemistry (IHC), Western Blot (WB), Flow Cytometry (FC) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation: |
Anti-FITC Antibody |
| Description: |
Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| French translation: |
anticorps |
| Gene target: |
Fas Ligand |
| Short name: |
Fas Ligand antibody (FITC) |
| Technique: |
Fluorescein, FITC |
| Label: |
FITC |
| Alternative name: |
member 6) Ligand (Antibody to) (fluorecein), Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |
| Identity: |
11936 |
| Gene: |
FASLG |
More about : FASLG |
| Long gene name: |
Fas ligand |
| Synonyms gene: |
APT1LG1 TNFSF6 |
| Synonyms gene name: |
member 6 Fas ligand (TNF superfamily, member 6) , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
FasL CD178 |
| Locus: |
1q24, 3 |
| Discovery year: |
1994-12-09 |
| GenBank acession: |
U11821 |
| Entrez gene record: |
356 |
| Pubmed identfication: |
7826947 9022072 |
| Classification: |
Endogenous ligands Tumor necrosis factor superfamily CD molecules Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000034841 |
| Locus Specific Databases: |
FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base) LRG_58 |