| Alternative name 1: |
Clone: 46E5, IHC/WB, Mab anti-Human, paraffin, Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) |
| Alternative name 2: |
Clone: 46E5, IHC/WB, Mab antibody-Human, paraffin, Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) |
| Alternative name 3: |
Clone: 46E5, IHC/WB, Mab antibody-Homo sapiens, paraffin, Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) |
| Alternative name 4: |
anti-Tissue Inhibitor of Matrix Metalloproteinase 2 TIMP2 Clone: 46E5 C/ |
| Alternative name 5: |
Tissue Inhibitor of Matrix Metalloproteinase 2 TIMP2 Clone: 46E5 C/ |
| Clonality: |
Monoclonal Antibody |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
IHC/, Monoclonal paraffin, Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) 46E5 |
| Short name: |
IHC/, Mouse Monoclonal antibody- paraffin, Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) Clone: 46E5 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, paraffin |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
Immunohistochemistry/Western Blot, Mouse monoclonal (Antibody to)-H, clonality: 46E5, paraffin, sapiens, Tissue suppressor on Matrix Metalloproteinase 2 (TIMP metallopeptidase inhibitor 2) |
| Alternative technique: |
murine |
| Alternative to gene target: |
BT, CSC-21K and DDC8, Extracellular, TIMP2 and IDBG-70963 and ENSG00000035862 and 7077, Timp2 and IDBG-214632 and ENSMUSG00000017466 and 21858, metal ion binding, this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007417 and central nervous system development and biological process this GO :0007568 and aging and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0008152 and metabolic process and biological process this GO :0008191 and metalloendopeptidase inhibitor activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009986 and cell surface and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030426 and growth cone and cellular component this GO :0030814 and regulation of cAMP metabolic process and biological process this GO :0032487 and regulation of Rap protein signal transduction and biological process this GO :0034097 and response to cytokine and biological process this GO :0042493 and response to drug and biological process this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043408 and regulation of MAPK cascade and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045762 and positive regulation of adenylate cyclase activity and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0046580 and negative regulation of Ras protein signal transduction and biological process this GO :0046872 and metal ion binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071310 and cellular response to organic substance and biological process, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0008047 : enzyme activator activity and also this GO :0008191 : metalloendopeptidase inhibitor activity and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008047 : enzyme activator activity, this GO :0008191 : metalloendopeptidase inhibitor activity, this GO :0046872 : metal ion binding, 52974 and IDBG-642791 and ENSBTAG00000010899 and 282093, TIMP metallopeptidase inhibitor 2 |
| Identity: |
11821 |
| Gene: |
TIMP2 |
More about : TIMP2 |
| Long gene name: |
TIMP metallopeptidase inhibitor 2 |
| Synonyms gene name: |
tissue inhibitor of metalloproteinase 2 |
| Synonyms: |
CSC-21K |
| Locus: |
17q25, 3 |
| Discovery year: |
1992-06-18 |
| Entrez gene record: |
7077 |
| Pubmed identfication: |
1427908 |
| RefSeq identity: |
NM_003255 |
| Classification: |
Tissue inhibitor of metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000154517 |