| known also as: |
Insulin receptor), beta subunit (INSR, Anti-a-Insulin Receptor |
| known also as: |
Insulin receptor), beta subunit (INSR, a-Insulin Receptor |
| known also as: |
Insulin receptor), beta subunit (INSR, a-Insulin Receptor |
| known also as: |
beta subunit, a-Insulin Receptor |
| known also as: |
Insulin receptor), beta subunit (INSR, Anti -a-Insulin Receptor |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
Species Crossreactivity, beta subunit, Recognizes human a-Insulin Receptor |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 150mM sodium chloride, pH 7, 05% sodium azide, 1M Tris-glycine, 4, Supplied as a liquid in 0 |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
Insulin receptor), beta subunit (INSR, a-Insulin Receptor |
| Short name: |
Insulin receptor) Antibody, beta subunit (INSR, a-Insulin Receptor |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Insulin receptor) (Antibody to), b functionnal sequence (insulin receptor, a-Insulin Receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CD220 and HHF5, Cell surfaces, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008544 and epidermis development and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, INSR and IDBG-22529 and ENSG00000171105 and 3643, Insr and IDBG-129570 and ENSMUSG00000005534 and 16337, this GO :0000187 and activation of MAPK activity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005009 and insulin-activated receptor activity and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005899 and insulin receptor complex and cellular component this GO :0005901 and caveola and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006355 and regulation of transcription, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0005009 : insulin-activated receptor activity and also this GO :0005159 : insulin-like growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005525 : GTP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0005009 : insulin-activated receptor activity, this GO :0005159 : insulin-like growth factor receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005525 : GTP binding, this GO :0016772 : transferase activity, this GO :0031994 : insulin-like growth factor I binding, this GO :0031995 : insulin-like growth factor II binding, this GO :0043548 : phosphatidylinositol 3-kinase binding, this GO :0043559 : insulin binding, this GO :0043560 : insulin receptor substrate binding, this GO :0051425 : PTB domain binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031994 : insulin-like growth factor I binding and also this GO :0031995 : insulin-like growth factor II binding and also this GO :0043548 : phosphatidylinositol 3-kinase binding and also this GO :0043559 : insulin binding and also this GO :0043560 : insulin receptor substrate binding and also this GO :0051425 : PTB domain binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019087 and transformation of host cell by virus and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030238 and male sex determination and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031017 and exocrine pancreas development and biological process this GO :0031994 and insulin-like growth factor I binding and molecular function this GO :0031995 and insulin-like growth factor II binding and molecular function this GO :0032147 and activation of protein kinase activity and biological process this GO :0032148 and activation of protein kinase B activity and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043559 and insulin binding and molecular function this GO :0043560 and insulin receptor substrate binding and molecular function this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045821 and positive regulation of glycolytic process and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045995 and regulation of embryonic development and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048639 and positive regulation of developmental growth and biological process this GO :0051290 and protein heterotetramerization and biological process this GO :0051425 and PTB domain binding and molecular function this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060267 and positive regulation of respiratory burst and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071363 and cellular response to growth factor stimulus and biological process, 63550 and IDBG-643606 and ENSBTAG00000012687 and 408017, insulin receptor |
| Identity: |
6091 |
| Gene: |
INSR |
More about : INSR |
| Long gene name: |
insulin receptor |
| Synonyms: |
CD220 |
| Locus: |
19p13, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M10051 |
| Entrez gene record: |
3643 |
| Pubmed identfication: |
2983222 |
| Classification: |
CD molecules Fibronectin type III domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000181992 |