| known also as: |
B Lymphocyte Serine/threonine-protein Kinase, BL44, GCK, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, RAB8IP), Rab8-interacting Protein, Anti-Germinal Center Kinase (GC Kinase |
| known also as: |
B Lymphocyte Serine/threonine-protein Kinase, BL44, GCK, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, RAB8IP), Rab8-interacting Protein, Germinal Center Kinase (GC Kinase |
| known also as: |
B Lymphocyte Serine/threonine-protein Kinase, BL44, GCK, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, RAB8IP), Rab8-interacting Protein, Germinal Center Kinase (GC Kinase |
| known also as: |
Germinal Center Kinase |
| known also as: |
B Lymphocyte Serine/threonine-protein Kinase, BL44, GCK, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, RAB8IP), Rab8-interacting Protein, Anti -Germinal Center Kinase (GC Kinase |
| Other names: |
N/A, germinal center kinase |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Monkey, Mouse, Rat, Human |
| Specificity and cross-reactivity: |
Does not crossreact with HPK or other members of the GCK family, Species Crossreactivity: mouse, monkey, rat, Recognizes endogenous levels of total human GCK protein at 91kD |
| Purification method: |
Affinity Purified by protein A and peptide affinity chromatography |
| Form/Appearance: |
0, 150mM sodium chloride, 50% glycerol, pH 7, 1mg/ml BSA, 5, Supplied as a liquid in 10mM sodium HEPES |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage, For maximum recovery of product, For optimal long term storage, Further dilutions can be made in assay buffer, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
B Lymphocyte Serine/threonine-protein Kinase, BL44, GCK, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, RAB8IP), Rab8-interacting Protein, Germinal Center Kinase (GC Kinase |
| Short name: |
B Lymphocyte Serine/threonine-protein Kinase, BL44, GCK, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, RAB8IP) Antibody, Rab8-interacting Protein, Germinal Center Kinase (GC Kinase |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
B Lymphocyte Serine/threonine-protein phosphorylation catalyst, BL44, GCK, MAPK/ERK phosphorylation catalyst Kinase phosphorylation catalyst 2, MEK phosphorylation catalyst Kinase 2, MEKKK 2, Mitogen-activated Protein phosphorylation catalyst Kinase phosphorylation catalyst Kinase 2, RAB8IP) (Antibody to), Rab8-interacting Protein, mitogen-activated protein phosphorylation catalyst kinase phosphorylation catalyst kinase 2, Germinal central phosphorylation catalyst (GC phosphorylation catalyst |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BL44 and GCK and RAB8IP, MAP4K2 and IDBG-55181 and ENSG00000168067 and 5871, MAP4K2 and IDBG-643979 and ENSBTAG00000001037 and 520058, Map4k2 and IDBG-135906 and ENSMUSG00000024948 and 26412, Plasma membranes, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000185 and activation of MAPKKK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0006468 and protein phosphorylation and biological process this GO :0006903 and vesicle targeting and biological process this GO :0006955 and immune response and biological process this GO :0007254 and JNK cascade and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005083 : small GTPase regulator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005083 : small GTPase regulator activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0031435 : mitogen-activated protein kinase kinase kinase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031435 : mitogen-activated protein kinase kinase kinase binding, transferring phosphorus-containing groups and molecular function this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0045087 and innate immune response and biological process this GO :0046330 and positive regulation of JNK cascade and biological process, mitogen-activated protein kinase kinase kinase kinase 2 |
| Identity: |
6864 |
| Gene: |
MAP4K2 |
More about : MAP4K2 |
| Long gene name: |
mitogen-activated protein kinase kinase kinase kinase 2 |
| Synonyms gene: |
RAB8IP |
| Synonyms: |
GCK BL44 |
| Locus: |
11q13, 1 |
| Discovery year: |
1997-08-18 |
| GenBank acession: |
BC047865 |
| Entrez gene record: |
5871 |
| Pubmed identfication: |
7515885 |
| RefSeq identity: |
NM_004579 |
| Classification: |
Mitogen-activated protein kinase kinase kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000045328 |