| Also known as: |
CD171 |
| Other names: |
CD_antigen: CD171, L1 cell adhesion molecule, Neural cell adhesion molecule L1, antigen identified by monoclonal antibody R1, neural cell adhesion molecule L1, neural cell adhesion molecule L1 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
L1CAM |
| Other gene names: |
CAML1, CAML1, CD171, HSAS, HSAS1, L1CAM, MASA, MIC5, MIC5, N-CAM-L1, N-CAM-L1, N-CAML1, NCAM-L1, NCAM-L1, S10, SPG1, L1CAM |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
SPM275 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
2) MASA (mental retardation, Expression of L1 protein is restricted to tissues arising from neuroectoderm, It binds to tumors of neuroectodermal and glial origin e, It does not bind to pediatric or adult brain, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The L1, The L1CAM gene, This MAb is useful in the identification of primitive neuroectodermal tumors, This particular antibody might cross react with speacies outside of the listed ones, and 3) SPG1 (spastic paraplegia), and adducted thumbs), and neural migration as well as in mediating neuronal differentiation, aphasia, fasciculation, identified as L1 cell adhesion molecule, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, neuroblastoma and Schwannomas, shuffling gait, which is located in Xq28, Recognizes a cell surface protein of 220-240kDa, g |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Gene target: |
CD171/ NCAM-L1 |
| Short name: |
CD171/ NCAM-L1 |
| Alternative name: |
CD171/ NCAM-L1 |
| Identity: |
6470 |
| Gene: |
L1CAM |
More about : L1CAM |
| Long gene name: |
L1 cell adhesion molecule |
| Synonyms gene: |
HSAS1 SPG1 HSAS MASA MIC5 S10 |
| Synonyms gene name: |
antigen identified by monoclonal antibody R1 |
| Synonyms: |
CD171 |
| Locus: |
Xq28 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
M74387 |
| Entrez gene record: |
3897 |
| RefSeq identity: |
NM_024003 |
| Classification: |
I-set domain containing CD molecules Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000024221 |
| Locus Specific Databases: |
Manchester LOVD LOVD - Leiden Open Variation Database LRG_14 , Mental Retardation database NGRL |