| Also known as: |
CD31 |
| Other names: |
CD31 antigen, CD_antigen: CD31, EndoCAM, GPIIA', PECA1, Platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule, platelet/endothelial cell adhesion molecule 1, platelet endothelial cell adhesion molecule |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PECAM1 |
| Other gene names: |
CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, PECAM-1, PECAM1, endoCAM, PECAM1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
JC/70A |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Cynomolgus Monkey, Does not react with Rat (Rattus norvegicus) and pig, Due to limited knowledge and inability for testing each and every species, Rabbit (Oryctolagus cuniculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells, CD31 MAb reacts with normal, CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare, The level of CD31 expression can help to determine the degree of tumor angiogenesis, This particular antibody might cross react with speacies outside of the listed ones, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence, and malignant endothelial cells which make up blood vessel lining, benign, CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD31/ PECAM-1 |
| Short name: |
CD31/ PECAM-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD31/ PECAM-1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8823 |
| Gene: |
PECAM1 |
More about : PECAM1 |
| Long gene name: |
platelet and endothelial cell adhesion molecule 1 |
| Synonyms gene name: |
platelet/endothelial cell adhesion molecule 1 |
| Synonyms: |
CD31 |
| Synonyms name: |
CD31 antigen |
| Locus: |
17q23, 3 |
| Discovery year: |
1995-11-29 |
| GenBank acession: |
L34631 M37780 |
| Entrez gene record: |
5175 |
| Pubmed identfication: |
8661055 1690453 |
| RefSeq identity: |
NM_000442 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000175829 |