| Also known as: |
CD20 |
| Other names: |
B-lymphocyte antigen CD20, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, CD20 antigen, CD20 receptor, CD_antigen: CD20, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, leukocyte surface antigen Leu-16, member 1, membrane-spanning 4-domains, subfamily A, B-lymphocyte antigen CD20 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MS4A1 |
| Other gene names: |
B1, Bp35, CD20, CD20, CVID5, LEU-16, MS4A1, MS4A2, S7, MS4A1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG2a |
| Clone: |
B9E9 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
B cell localization in tissues and B lymphocyte purification by immunosorbent methods, B lymphocyte detection in peripheral blood, B9E9 recognizes extracellular domain of CD20, CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells, CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation, Code CD20, It acts as a calcium channel involved in B-cell activation and cell cycle progression, Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1, This MAb can be used for immunophenotyping of leukemia and malignant cells, This particular antibody might cross react with speacies outside of the listed ones, being absent from all other leukocytes and tissues, identified as CD20 (Workshop V, 12), Recognizes a protein of 33-37kDa |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD20 |
| Short name: |
CD20 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD20 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7315 |
| Gene: |
MS4A1 |
More about : MS4A1 |
| Long gene name: |
membrane spanning 4-domains A1 |
| Synonyms gene: |
CD20 |
| Synonyms gene name: |
member 1 , membrane-spanning 4-domains, subfamily A |
| Synonyms: |
B1 Bp35 MS4A2 |
| Locus: |
11q12, 2 |
| Discovery year: |
1989-05-23 |
| GenBank acession: |
M27394 |
| Entrez gene record: |
931 |
| Pubmed identfication: |
2448768 |
| Classification: |
CD molecules Membrane spanning 4-domains |
| Havana BLAST/BLAT: |
OTTHUMG00000167614 |
| Locus Specific Databases: |
LRG_140 |