| Also known as: |
Renal Cell Carcinoma |
| Other names: |
CA-IX, CA-IX, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, Carbonic anhydrase IX, Membrane antigen MN, P54/58N, P54/58N, RCC-associated antigen G250, RCC-associated antigen G250, RCC-associated protein G250, Renal cell carcinoma-associated antigen G250, carbonate dehydratase IX, carbonic anhydrase 9, carbonic anhydrase IX, carbonic dehydratase, membrane antigen MN, pMW1, pMW1, renal cell carcinoma-associated antigen G250, carbonic anhydrase 9 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CA9 |
| Other gene names: |
CA-IX, CA9, CAIX, CAIX, G250, MN, MN, RCC-associated antigen G250, CA9 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG2b |
| Clone: |
SPM314 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Horse, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
HMFG, In normal kidney, It shows no significant cross-reactivity with other carbohydrate determinants, Its epitope resides in the carbohydrate domain of gp200, Reportedly, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation, This particular antibody might cross react with speacies outside of the listed ones, and AB blood group antigens, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule, epithelial membrane antigen, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, identified as carbonic anhydrase IX (CAIX/gp200), such as the Lewis blood group antigens, Recognizes a glycoprotein of ~200kDa |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Gene target: |
Renal Carcinoma/ gp200 (Carbonic Anhydrase IX) |
| Short name: |
Renal Cell Carcinoma/ gp200 (Carbonic Anhydrase IX) |
| Alternative name: |
Renal cellular Carcinoma/ gp200 (Carbonic Anhydrase IX) |