| Also known as: |
Myogenin |
| Other names: |
Class C basic helix-loop-helix protein 3, Myf-4, Myogenic factor 4, Myogenin, bHLHc3, class C basic helix-loop-helix protein 3, myogenic factor 4, myogenin, myogenin (myogenic factor 4), myogenin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MYOG |
| Other gene names: |
BHLHC3, MYF4, MYF4, MYOG, Myf-4, bHLHc3, bHLHc3, myf-4, MYOG |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, kappa + IgG1, IgG1 |
| Clone: |
MGN185 + F5D |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Cat, Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Pig, Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, Myf-5, MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes, MyoD family members share about 80% amino acid homology in their bHLH motifs, Positive nuclear staining may occur in Wilms' tumor, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif, This particular antibody might cross react with speacies outside of the listed ones, and MRF4 (also known as herculinor Myf-6), and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas, Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Gene target: |
Myogenin |
| Short name: |
Myogenin |
| Alternative name: |
Myogenin |
| Identity: |
7612 |
| Gene: |
MYOG |
More about : MYOG |
| Long gene name: |
myogenin |
| Synonyms gene: |
MYF4 |
| Synonyms gene name: |
myogenin (myogenic factor 4) |
| Synonyms: |
bHLHc3 |
| Synonyms name: |
myogenic factor 4 |
| Locus: |
1q32, 1 |
| Discovery year: |
1990-11-20 |
| GenBank acession: |
BC053899 |
| Entrez gene record: |
4656 |
| Pubmed identfication: |
10329008 |
| RefSeq identity: |
NM_002479 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000042127 |