| known also as: |
Clade D, Member 1) (Biotin), Anti-SERPIND1 (Serine/Cysteine Proteinase Inhibitor |
| known also as: |
Clade D, Member 1) (Biotin), SERPIND1 (Serine/Cysteine Proteinase Inhibitor |
| known also as: |
Clade D, Member 1) (Biotin), SERPIND1 (Serine/Cysteine Proteinase Inhibitor |
| known also as: |
SERPIND1 |
| known also as: |
Clade D, Member 1) (Biotin), Anti -SERPIND1 (Serine/Cysteine Proteinase Inhibitor |
| Other names: |
HC-II, HLS2, Heparin cofactor 2, Heparin cofactor II, OTTHUMP00000198450, OTTHUMP00000198451, Protease inhibitor leuserpin-2, Serpin D1, clade D (heparin cofactor), clade D (heparin cofactor), heparin cofactor 2, leuserpin 2, member 1, member 1, protease inhibitor leuserpin-2, serine (or cysteine) proteinase inhibitor, serpin D1, serpin peptidase inhibitor, SERPIND1 |
| Other gene names: |
D22S673, HC2, HCF2, HCF2, HCII, HLS2, LS2, SERPIND1, SERPIND1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Selected for use as a detection antibody in human Serpin D1 Western Blots |
| Purification method: |
Affinity Purified by human Serpin D1 affinity chromatography and then biotinylated |
| Form/Appearance: |
150mM sodium chloride) containing 0, 40-50% glycerol, If 1ml of buffer is us, Reconstitute with sterile TBS, pH 7, 1% BSA, 2um filtered solution in PBS containing 50ug of BSA per 1ug of antibody, 3 (20mM Trizma base, Supplied as a lyophilized powder from a 0 |
| Storage and shipping: |
For maximum recovery of product, Further dilutions can be made in assay buffer, Reconstitute to nominal volume by adding sterile TBS with 40-50% glycerol and For optimal long term storage, Reconstituted product is stable for 12 months productone should be stored at -20 degrees Celsius, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Lyophilized powder Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase |
| Conjugation: |
Biotinylated |
| Gene target: |
Clade D, Member 1), SERPIND1 (Serine/Cysteine Proteinase Inhibitor |
| Short name: |
Clade D, Member 1) ( ), SERPIND1 (Serine/Cysteine Proteinase Inhibitor |
| Label: |
Biotin |
| Alternative name: |
Clade D, Member 1) (biotinilated), clade D (heparin cofactor), member 1 (Serine/Cysteine Proteinase suppressor, serpin peptidase inhibitor |
| Alternative to gene target: |
D22S673 and HC2 and HCF2 and HCII and HLS2 and LS2 and THPH10, Extracellular, SERPIND1 and IDBG-1808 and ENSG00000099937 and 3053, SERPIND1 and IDBG-637655 and ENSBTAG00000013973 and 100125764, Serpind1 and IDBG-138819 and ENSMUSG00000022766 and 15160, clade D (heparin cofactor), heparin binding, member 1, this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006935 and chemotaxis and biological process this GO :0007596 and blood coagulation and biological process this GO :0008201 and heparin binding and molecular function this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030162 and regulation of proteolysis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004866 : endopeptidase inhibitor activity, this GO :0004866 : endopeptidase inhibitor activity and also this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0008201 : heparin binding, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0008201 : heparin binding, serpin peptidase inhibitor |
| Identity: |
4838 |
| Gene: |
SERPIND1 |
More about : SERPIND1 |
| Long gene name: |
serpin family D member 1 |
| Synonyms gene: |
HCF2 |
| Synonyms gene name: |
clade D (heparin cofactor), clade D (heparin cofactor), member 1 , member 1 serpin peptidase inhibitor, serine (or cysteine) proteinase inhibitor |
| Synonyms: |
HC-II HLS2 HC2 D22S673 |
| Synonyms name: |
heparin cofactor II heparin cofactor 2 |
| Locus: |
22q11, 21 |
| Discovery year: |
1988-05-31 |
| GenBank acession: |
M12849 |
| Entrez gene record: |
3053 |
| Pubmed identfication: |
1671335 24172014 |
| RefSeq identity: |
NM_000185 |
| Classification: |
Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000150755 |
| Locus Specific Databases: |
LRG_594 |