| known also as: |
X Chromosome linked Inhibitor of Apoptosis Associated Factor 1), Anti-XIAP Associated Factor 1 (XAF1 |
| known also as: |
X Chromosome linked Inhibitor of Apoptosis Associated Factor 1), XIAP Associated Factor 1 (XAF1 |
| known also as: |
X Chromosome linked Inhibitor of Apoptosis Associated Factor 1), XIAP Associated Factor 1 (XAF1 |
| known also as: |
XIAP Associated Factor 1 |
| known also as: |
X Chromosome linked Inhibitor of Apoptosis Associated Factor 1), Anti -XIAP Associated Factor 1 (XAF1 |
| Other names: |
BIRC4 binding protein, BIRC4-binding protein, BIRC4-binding protein, XIAP associated factor 1, XIAP-associated factor 1, XIAP-associated factor 1, XIAP-associated factor 1 isoform 1 |
| Other gene names: |
BIRC4BP, BIRC4BP, HSXIAPAF1, XAF1, XIAPAF1, XIAPAF1, XAF1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Recognizes human XIAP Associated Factor 1 (XAF1) |
| Purification method: |
Affinity Purified by Protein G affinity chromatography |
| Form/Appearance: |
0, 02% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile glycerol (40-50%), aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunohistochemistry (IHC), Western Blot (WB) |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
X Chromosome linked Inhibitor of Associated Factor 1), XIAP Associated Factor 1 (XAF1 |
| Short name: |
X Chromosome linked Inhibitor of Apoptosis Associated Factor 1) Antibody, XIAP Associated Factor 1 (XAF1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
X Chromosome linked suppressor on programmed cellular destruction Associated Factor 1) (Antibody to), X-linked inhibitor on apoptosis Associated Factor 1 (X-linked inhibitor on apoptosis associated factor 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
X-linked inhibitor of apoptosis, XAF1 and IDBG-22619 and ENSG00000132530 and 54739, XAF1 and IDBG-633696 and ENSBTAG00000011343 and 509740, XIAP and IDBG-85142 and ENSG00000101966 and 331, Xaf1 and IDBG-196515 and ENSMUSG00000040483 and 327959, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, nuclei, nuclei, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016055 and Wnt signaling pathway and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030510 and regulation of BMP signaling pathway and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0055070 and copper ion homeostasis and biological process this GO :0070424 and regulation of nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1902530 and positive regulation of protein linear polyubiquitination and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0043027 : cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0031333 and negative regulation of protein complex assembly and biological process this GO :0035456 and response to interferon-beta and biological process this GO :0060337 and type I interferon signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding, this GO :0008270 : zinc ion binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0043027 : cysteine-type endopeptidase inhibitor activity involved in apoptotic process, zinc ion binding, XIAP associated factor 1 |
| Identity: |
30932 |
| Gene: |
XAF1 |
More about : XAF1 |
| Long gene name: |
XIAP associated factor 1 |
| Synonyms: |
BIRC4BP XIAPAF1 HSXIAPAF1 |
| Locus: |
17p13, 2 |
| Discovery year: |
2008-03-04 |
| GenBank acession: |
X99699 |
| Entrez gene record: |
54739 |
| Pubmed identfication: |
12029096 11175744 |
| RefSeq identity: |
NM_017523 |
| Havana BLAST/BLAT: |
OTTHUMG00000177908 |