| Also known as: |
Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) |
| Other names: |
CSC-21K, Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2, metalloproteinase inhibitor 2, tissue inhibitor of metalloproteinase 2, tissue inhibitor of metalloproteinases 2, metalloproteinase inhibitor 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TIMP2 |
| Other gene names: |
CSC-21K, DDC8, TIMP-2, TIMP2, TIMP2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
3A4 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Chicken, Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Pig, Rabbit (Oryctolagus cuniculus), Zebrafish, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A/G Chromatography |
| Form/Appearance: |
08% sodium azide, Provided as solution in phosphate buffered saline with 0 |
| Storage and shipping: |
Aliquot to avoid freeze/thaw cycles, Product should be stored the antibody should be stored at -20 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC), Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Gene target: |
Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) |
| Short name: |
Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Tissue suppressor on Matrix Metalloproteinase 2 (TIMP metallopeptidase inhibitor 2) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, CSC-21K and DDC8, Extracellular, TIMP2 and IDBG-70963 and ENSG00000035862 and 7077, Timp2 and IDBG-214632 and ENSMUSG00000017466 and 21858, metal ion binding, this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007417 and central nervous system development and biological process this GO :0007568 and aging and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0008152 and metabolic process and biological process this GO :0008191 and metalloendopeptidase inhibitor activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009986 and cell surface and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030426 and growth cone and cellular component this GO :0030814 and regulation of cAMP metabolic process and biological process this GO :0032487 and regulation of Rap protein signal transduction and biological process this GO :0034097 and response to cytokine and biological process this GO :0042493 and response to drug and biological process this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043408 and regulation of MAPK cascade and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045762 and positive regulation of adenylate cyclase activity and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0045930 and negative regulation of mitotic cell cycle and biological process this GO :0046580 and negative regulation of Ras protein signal transduction and biological process this GO :0046872 and metal ion binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071310 and cellular response to organic substance and biological process, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0008047 : enzyme activator activity and also this GO :0008191 : metalloendopeptidase inhibitor activity and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008047 : enzyme activator activity, this GO :0008191 : metalloendopeptidase inhibitor activity, this GO :0046872 : metal ion binding, 52974 and IDBG-642791 and ENSBTAG00000010899 and 282093, TIMP metallopeptidase inhibitor 2 |
| Identity: |
11821 |
| Gene: |
TIMP2 |
More about : TIMP2 |
| Long gene name: |
TIMP metallopeptidase inhibitor 2 |
| Synonyms gene name: |
tissue inhibitor of metalloproteinase 2 |
| Synonyms: |
CSC-21K |
| Locus: |
17q25, 3 |
| Discovery year: |
1992-06-18 |
| Entrez gene record: |
7077 |
| Pubmed identfication: |
1427908 |
| RefSeq identity: |
NM_003255 |
| Classification: |
Tissue inhibitor of metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000154517 |