| known also as: |
FLK-1, FLK1, Fetal liver kinase 1, KDR, KDR) (VEGFR2, KRD1, Kinase NYK, Kinase insert domain receptor, Ly73, Protein tyrosine kinase receptor, Protein-tyrosine kinase receptor flk-1, VEGFR 2, VEGFR-2, Anti-VEGFR-2 (Vascular Endothelial Growth Factor Receptor 2 |
| known also as: |
FLK-1, FLK1, Fetal liver kinase 1, KDR, KDR) (VEGFR2, KRD1, Kinase NYK, Kinase insert domain receptor, Ly73, Protein tyrosine kinase receptor, Protein-tyrosine kinase receptor flk-1, VEGFR 2, VEGFR-2, VEGFR-2 (Vascular Endothelial Growth Factor Receptor 2 |
| known also as: |
FLK-1, FLK1, Fetal liver kinase 1, KDR, KDR) (VEGFR2, KRD1, Kinase NYK, Kinase insert domain receptor, Ly73, Protein tyrosine kinase receptor, Protein-tyrosine kinase receptor flk-1, VEGFR 2, VEGFR-2, VEGFR-2 (Vascular Endothelial Growth Factor Receptor 2 |
| known also as: |
VEGFR-2 |
| known also as: |
FLK-1, FLK1, Fetal liver kinase 1, KDR, KDR) (VEGFR2, KRD1, Kinase NYK, Kinase insert domain receptor, Ly73, Protein tyrosine kinase receptor, Protein-tyrosine kinase receptor flk-1, VEGFR 2, VEGFR-2, Anti -VEGFR-2 (Vascular Endothelial Growth Factor Receptor 2 |
| Other names: |
FLK-1, Fetal liver kinase 1, Kinase insert domain receptor, OTTHUMP00000158928, Protein-tyrosine kinase receptor flk-1, Vascular endothelial growth factor receptor 2, fetal liver kinase 1, fetal liver kinase-1, kinase insert domain receptor (a type III receptor tyrosine kinase), protein-tyrosine kinase receptor Flk-1, soluble VEGFR2, tyrosine kinase growth factor receptor, vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor 2 |
| Other gene names: |
CD309, FLK1, FLK1, KDR, VEGFR, VEGFR2, KDR |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Mouse, Host: Rabbit |
| Species reactivity: |
Mouse |
| Specificity and cross-reactivity: |
Human reactivity is expected based on sequence homology, Identi es the ~230kD mature form of VEGFR-2, Reactivity is con rmed with mouse SVEC 4-10 cell lysates, Rrecognizes mouse VEGF Receptor-2 |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, pH 7, 05% sodium azide, 4, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile glycerol (40-50%), aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB), ELISA (EL/EIA) |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
FLK-1, FLK1, Fetal liver kinase 1, KDR, KDR) (VEGFR2, KRD1, Kinase NYK, Kinase insert domain receptor, Ly73, Protein tyrosine kinase receptor, Protein-tyrosine kinase receptor flk-1, VEGFR 2, VEGFR-2, VEGFR-2 (Vascular Endothelial Growth Factor Receptor 2 |
| Short name: |
FLK-1, FLK1, Fetal liver kinase 1, KDR, KDR) (VEGFR2, KRD1, Kinase NYK, Kinase insert domain receptor, Ly73, Protein tyrosine kinase receptor, Protein-tyrosine kinase receptor flk-1, VEGFR 2, VEGFR-2, VEGFR-2 (Vascular Endothelial Growth Factor Receptor 2 |
| Alternative name: |
FLK-1, FLK1, Fetal liver phosphorylation catalyst 1, KRD1, Ly73, Protein tyrosine phosphorylation catalyst receptor, Protein-tyrosine phosphorylation catalyst receptor flk-1, VEGFR 2, VEGFR-2, kinase insert domain receptor (a type III receptor tyrosine kinase), kinase insert domain receptor (a type III receptor tyrosine kinase)) (VEGFR2, phosphorylation catalyst NYK, phosphorylation catalyst insert domain receptor, VEGFR-2 (Vascular Endothelial Growth Factor Receptor 2 |
| Alternative to gene target: |
CD309 and FLK1 and VEGFR and VEGFR2, KDR and IDBG-19161 and ENSG00000128052 and 3791, KDR and IDBG-642352 and ENSBTAG00000000782 and 407170, Kdr and IDBG-172240 and ENSMUSG00000062960 and 16542, nuclei, this GO :0001525 and angiogenesis and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001945 and lymph vessel development and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003158 and endothelium development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005021 and vascular endothelial growth factor-activated receptor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016032 and viral process and biological process this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0005021 : vascular endothelial growth factor-activated receptor activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0005021 : vascular endothelial growth factor-activated receptor activity, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019838 : growth factor binding, this GO :0038085 : vascular endothelial growth factor binding, this GO :0051879 : Hsp90 protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019838 : growth factor binding and also this GO :0038085 : vascular endothelial growth factor binding and also this GO :0051879 : Hsp90 protein binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030054 and cell junction and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030324 and lung development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0035162 and embryonic hemopoiesis and biological process this GO :0035584 and calcium-mediated signaling using intracellular calcium source and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0038084 and vascular endothelial growth factor signaling pathway and biological process this GO :0038085 and vascular endothelial growth factor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043129 and surfactant homeostasis and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045121 and membrane raft and cellular component this GO :0045165 and cell fate commitment and biological process this GO :0045446 and endothelial cell differentiation and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048469 and cell maturation and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050927 and positive regulation of positive chemotaxis and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0051879 and Hsp90 protein binding and molecular function this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0055074 and calcium ion homeostasis and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071944 and cell periphery and cellular component this GO :0097443 and sorting endosome and cellular component this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process this GO :2001214 and positive regulation of vasculogenesis and biological process, kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Identity: |
6307 |
| Gene: |
KDR |
More about : KDR |
| Long gene name: |
kinase insert domain receptor |
| Synonyms gene name: |
kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Synonyms: |
FLK1 VEGFR VEGFR2 CD309 |
| Synonyms name: |
vascular endothelial growth factor receptor 2 fetal liver kinase 1 |
| Locus: |
4q12 |
| Discovery year: |
1991-07-10 |
| GenBank acession: |
AF035121 |
| Entrez gene record: |
3791 |
| Pubmed identfication: |
1417831 |
| Classification: |
I-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000128734 |
| Locus Specific Databases: |
The Globin Gene Server |