| Catalog number: | bsm-51289M |
|---|---|
| Price: | 486 € |
| Supplier: | MBS mono |
| Product name: | Tyro3 (1444CT895.86.31) Monoclonal Antibody |
| Quantity: | 100ul |
| Related search: |
| Long name: | 31) Monoclonal Antibody, 86, Tyro3 (1444CT895 |
|---|---|
| Also known as: | 31) Monoclonal Antibody, 86, Tyro3 (1444CT895 |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | Tyro3 |
| Specificity: | This is a highly specific antibody against Tyro3 |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Monoclonal |
| Clone number: | 1444CT895, 31, 86 |
| Source: | This Tyro3 antibody is generated from a mouse immunized with a recombinant protein |
| Gene ID number: | 22174 |
| Swiss Prot: | P55144 |
| Tested Applications: | WB |
| Recommended dilutions: | WB(1:2000) |
| Cross reactivity: | Mouse |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Activates the AKT survival pathway, Following activation by ligand, Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules, Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, Regulates many physiological processes including cell survival, TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes, interacts with PIK3R1 and thereby enhances PI3-kinase activity, migration and differentiation, platelet aggregation and cytoskeleton reorganization, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6 |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | AI323366, Dtk, Etk-2, Rse, Sky, TK19-2, Tif, Tyro3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase TIF, Tyrosine-protein kinase receptor TYRO3, etk2/tyro3, tk19-1, Brt |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: | 31) Monoclonal, 86, Tyro3 (1444CT895 |
| Short name: | 31) Monoclonal Antibody, 86, Tyro3 (1444CT895 |
| Technique: | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | 31) monoclonal (Antibody to), 86, TYRO3 protein tyrosine kinase (1444CT895 |
| Alternative technique: | antibodies |
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